Senior Bioprocessing Scientist

Senior Bioprocessing Scientist

Final date to receive applications: 20 September 2026

Department: Edinburgh Centre

Employment Type: Permanent - Full Time

Location: Edinburgh

Purpose of Role:
The Senior Bioprocessing Scientist will apply in-depth technical expertise across a range of projects to support the development of bioprocesses by adapting manual 2D processes into closed and automated processes, using technologies including stirred-tank bioreactors and other closed processing systems, linking unit operations, and integrating state of the art automation and digitalisation technologies to reduce cost of manufacturing and strengthen supply for manufacture of ATMPs.

The role will be high profile, both within the organisation and outward facing to the Company’s stakeholders and Collaborators. As an active member of the CGT Catapult Scale Enabling Technology (SET) Edinburgh team, the Senior Bioprocessing Scientist will work closely with the London and Stevenage SET teams as well as the CGT Catapult Manufacturing Innovation Centres (MICs) in Stevenage and Braintree to, plan and deliver on commercial, collaborative and in-house process development projects to drive the Up-Stream Process (USP) development work, automation and control within the CGT Catapult portfolio.

• Provide subject matter expertise in bioprocessing of ATMPs including autologous and allogeneic products
• To engage and collaborate with CGT Catapult teams across different sites and disciplines
• Use of in-depth knowledge of ATMP process development, upstream bioprocessing, PAT and data analysis techniques to enable the delivery of process development and automation projects
• Drive towards integration of automation and digitalisation for cost of goods reduction by working with data, analytical, and IT teams
• Provide subject matter expertise in the planning and execution of laboratory work, the review of ATMP related products and processes, and the preparation of technical reports
• Provide leadership/ownership of laboratory activities associated with assigned USP development projects, including stock control, experimental design/planning/reporting, compliance with onsite procedures
• Support, engage and communicate effectively with internal and external stakeholders to disseminate newly established innovative capabilities to the wider UK industry
• Agree resource requirements and budgets with project sponsors, project managers and Lead Scientists
• Produce, review experimental plans, witness completed experiments in the ELN, ensure raw data is processed according to data integrity guidelines and stored according to company policies, producing and reviewing study reports
• Present data at conferences and meetings where appropriate
• Provide line management and leadership to junior team members and mentoring of scientists within the team
• Work with technology providers and organisations to ensure that the CGT Catapult is a leader in scalable, automated process development for ATMPs
• Support Lead Scientist in day to day operational management of the facility
• Drive continuous improvement initiatives to optimise operational, laboratory and administrative processes whilst enhancing efficiency
• Contribution to out of hours work as required, demonstrating flexibility to meet project and business needs

• Relevant experience gained within a commercial biotechnology, biopharmaceutical, advanced therapies, or life sciences environment is essential
• Experience in analytical assays such as flow cytometry, qPCR, metabolite profiling and cell counting is essential
• Demonstrable experience of executing agreed research independently with minimal supervision is essential
• Experience of bioprocessing data structuring, analysis and formatting is essential
• Experience in bioprocessing and scaling, including upstream processing using stir tank bioreactor and other cell culture technologies and techniques are essential, including DASbox, BioBLU, ambr
  250, Quantum Flex, univessel bioreactor systems, 2D/3D culture systems, cell handling (e.g. T-cells, NK-cells, HEK cells), cell thawing, expansion, differentiation and banking
• Proven experience in PSC cell bioprocessing, including the culture, expansion and optimisation of cells using 2D and 3D systems
• Proven experience of effectively delivering training and developing other team members
• Experience in conducting technical Genetically Modified Organisms risk assessments to ensure biosafety compliance
• Experience of designing end to end bioprocess workflows with a focus on automation and digitalisation to drive standardisation and process closure
• Experience in Health and Safety management, including generation of risk assessments and ensuring COSHH compliance, contribution to incidents and near miss investigations, safety inspections and audits, equipment safety with an interest in advancing knowledge through NEBOSH certification
• Experience of statistical tools such as method validation and/or Design of Experiments to…