Sr Technician, Downstream Process

GenScript Biotech Corporation (Stock Code: 1548.HK)

GenScript is a global biotechnology group founded in 2002, with an established presence across North America, Europe, Greater China, and the Asia Pacific. The company’s businesses encompass four major categories based on its leading gene synthesis technology, including a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.

Pro Bio, a subsidiary of GenScript, is a global CDMO offering end‑to‑end services from discovery to GMP for plasmids, antibodies, and cell & gene therapies. Pro Bio brings multidisciplinary expertise to accelerate development and manufacturing through customized, comprehensive services and has supported more than 150 IND approvals since October 2017.

The (Sr) Technician, Downstream Process will work within the Downstream Processing group and perform the following activities while executing downstream operations:

• Preparation of stock solutions, buffers, and filtration.
• Operation of all production equipment in the assigned functional area, including single‑use chromatography systems, chromatography columns, other disposable bioprocess equipment, and solution preparation equipment, as per written procedures.
• Support of relevant regulatory requirements and company Standard Operating Procedures (SOPs).

• Execute routine complex manufacturing assignments per written procedures, recognize deviations, and raise issues to management for resolution.
• Adhere to current Good Manufacturing Practices (cGMP) and SOPs.
• Perform routine microbial and mammalian purification; monitor chromatography and tangential flow filtration (TFF) systems during processing.
• Weigh and check raw materials, assemble process equipment, and monitor processes.
• Complete work instructions and maintain a clean‑room environment to comply with regulatory requirements.
• Authored solution preparation Master Batch Records (MBRs) by transferring technical information from scientific and development documents.
• Propose and route revisions to existing SOPs for functional area equipment.
• Become proficient on common bioprocessing equipment.
• Conduct safety and GMP self‑auditing walkthroughs, document observations, and track closure.
• Log and submit samples in the Laboratory Information Management System (LIMS); track results and compile data.
• Review own work for completeness on executed MBRs.
• Coordinate the tracking and return of executed records to the Quality department for review.
• Coordinate with Logistics to ensure needed materials are delivered to the production area timely and alert Logistics to shortfalls.
• Perform other tasks and assignments as needed and specified by management.

• Bachelor’s degree in science or engineering with 0–5 years relevant experience; or Associate’s degree with a minimum of three years; or high school diploma with a minimum of seven years of relevant experience.
• Demonstrated ability to follow written instructions and procedures.
• Strong attention to detail.
• Proficiency with Microsoft Office.
• Excellent verbal and written communication skills.
• Ability to work collaboratively as part of a team in a fast‑paced, matrixed environment.

Estimated pay range: $60,000 – $75,000 based on qualifications and experience.

GenScript USA Inc/Pro Bio Inc. is a proud equal‑opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. The company’s policy ensures equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./Pro Bio Inc. maintains a drug‑free workplace.