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Director, Neuroscience Portfolio Strategy

Job in Spring House, Montgomery County, Pennsylvania, 19477, USA
Listing for: J&J Family of Companies
Full Time position
Listed on 2026-08-22
Job specializations:
  • Business
    Corporate Strategy
Job Description & How to Apply Below
Location: Spring House

Director, Neuroscience Portfolio Strategy

Johnson & Johnson (J&J) is seeking a Director, Neuroscience Portfolio Strategy to be located in Titusville, NJ;
Raritan, NJ;
Spring House, PA;
San Diego, CA or Cambridge, MA.

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Neuroscience team tackles the world's toughest brain health challenges including multiple sclerosis, Alzheimer's disease, Parkinson's disease, myasthenia gravis, epilepsy, major depressive disorder, bipolar disorder, schizophrenia, and autism. This patient-focused team helps address some of the most complex diseases of our time.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Position Summary:

The Director, Neuroscience Portfolio Strategy is a key leader within the Neuroscience Portfolio Strategy and Integration (NPSI) organization and is responsible for helping shape the long-term strategic direction of Johnson & Johnson's Neuroscience portfolio. This individual serves as a strategic thought partner to Neuroscience senior leadership, driving portfolio prioritization, investment decision-making, innovation strategy, and enterprise-level planning across neurodegeneration, neuropsychiatry, ophthalmology, and emerging neuroscience opportunities.

The Director will work across Discovery, Development, Commercial, Business Development, External Innovation, Finance, Medical Affairs, and other cross-functional partners address a broad range of portfolio strategy questions, including evaluating portfolio opportunities, identifying areas for growth, assessing risks, and supporting integrated portfolio strategies that maximize long-term value and patient impact. The role requires scientific acumen, business strategy expertise, and strong leadership capability to influence complex decisions across all stages of the portfolio lifecycle.

As a leader within NPSI, the Director will help guide strategic planning efforts, facilitate portfolio governance discussions, support external innovation and business development assessments, and drive alignment across Neuroscience Disease Areas and Compound Development Teams. This individual will lead a small team and contribute to the continued evolution of Johnson & Johnson's Neuroscience strategy as the organization expands and diversifies its portfolio.

Key Responsibilities:

  • Maintain and grow a broad, deep, and dynamic understanding of internal strategic resources, including Neuroscience strategy, product development plans, Target Product Profiles, knowledge management systems, portfolio priorities, governance processes, and long-range planning inputs, as well as external strategic resources including competitive intelligence, market dynamics, regulatory precedent, policy developments, external innovation, and business development trends.
  • Lead strategic portfolio assessments and scenario planning activities to support investment decisions, resource allocation, portfolio prioritization, and long-range Neuroscience Therapeutic Area planning across neurodegeneration, neuropsychiatry, ophthalmology, and emerging areas of scientific opportunity.
  • Independently identify and evaluate opportunities to strengthen portfolio value through strategic prioritization, lifecycle planning, external innovation, business development assessments, risk mitigation, and organizational investments.
  • Actively partner with NPSI colleagues, Disease Area Leadership Teams, Compound Development Teams, and senior functional leaders to advise and drive program, portfolio, and disease area strategies, plans, objectives, and executive communications across the Neuroscience portfolio.
  • Partner across the development continuum to ensure portfolio strategies are aligned from discovery through late-stage development, regulatory milestones, commercialization planning, and lifecycle management.
  • Serve as a facilitator and trusted advisor in strategically complex, cross-functional discussions, including portfolio reviews, lifecycle management assessments, opportunity assessments, strategic process improvements, governance forums, and J&J Innovative Medicine-level portfolio discussions.
  • Build strong two-way partnerships across R&D, Commercial, Business Development, External Innovation, Medical Affairs, Competitive Intelligence, Data Science, Development, and Finance to advance Neuroscience portfolio objectives and enterprise priorities.
  • Act as a strategic thought partner for Neuroscience Therapeutic Area and Disease Area senior leaders, with the ability to confidently participate in and present to senior leadership forums.
  • Exhibit self-awareness, a learning mindset, and the ability to influence stakeholders from different functional backgrounds by clearly articulating the strategic value of portfolio recommendations,…
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