Principal Scientist​/Lab Manager, Clinical Pathology

Position Title: Clinical Pathology Laboratory Manager / Principal Scientist

Job Type: Full-time

The Clinical Pathology Laboratory Manager provides operational and technical leadership with scientific insights for the clinical pathology laboratory within the Nonclinical Drug Safety Department. The successful candidate will ensure accurate, timely, and compliant delivery of laboratory data, and collaborate with stakeholders across functions to support nonclinical studies and development decisions throughout the pipeline from early discovery to submissions and post‑marketing requirements.

This role reports to the head of the Clinical Pathology group.

• Manage day‑to‑day functions of the clinical pathology laboratory, including hematology, coagulation, clinical chemistry, urinalysis, and related areas in multiple nonclinical species (rodents and non‑rodents). This includes instrument operation and data generation on a rotating basis.
• Supervise laboratory personnel: hiring, onboarding, scheduling, performance reviews, and career development.
• Ensure appropriate staffing levels and competency through workforce planning and cross‑training.

• Ensure compliance with institutional policies in a regulated environment (Good Laboratory Practice).
• Oversee validation and documentation for new assays, instruments, and software updates.
• Monitor test performance, instrument functionality, and quality control (QC) metrics; respond to QC failures and implement corrective actions.
• Evaluate new technologies, reagents, and automation opportunities; lead implementation projects as needed.
• Promote and enforce a safe work environment, ensuring adherence to biosafety, chemical safety, and waste disposal regulations.
• Ensure staff are appropriately trained in safety policies and the use of personal protective equipment for laboratory operations.

• Serve as the primary point of contact between the laboratory and stakeholders.
• Prepare and present reports on laboratory performance, quality metrics, and improvement projects.
• Participate in multidisciplinary committees and contribute to laboratory strategy.

• Bachelor's degree in Medical Laboratory Science, Clinical Laboratory Science, Biology, Chemistry, or a related field.
• ASCP (MLS/MLT) or equivalent certification.
• Minimum of 10 years of clinical laboratory experience with at least 2 years in a supervisory or lead role in clinical pathology or equivalent sections.
• Strong knowledge of clinical laboratory operations, instrumentation, quality systems, and regulatory requirements (GLP).
• Proven leadership, communication, and team development skills.
• Proficiency with laboratory information systems (LIS) and electronic laboratory notebooks.

• Master's degree in clinical laboratory science or a related field.
• Prior experience in a hospital‑based or high‑volume clinical laboratory.

• Leadership and people management.
• Decision‑making and problem‑solving.
• Quality and regulatory focus.
• Resource optimization.
• Effective communication.
• Technical aptitude and continuous learning.

• Primarily laboratory environment with intermittent exposure to biological specimens, chemical reagents, and laboratory equipment noise.
• Requires use of PPE and adherence to safety protocols.
• On‑site office and laboratory‑based position.

• Chemical Safety
• Clinical Judgment
• Clinical Pathology
• Collaborative Communications
• Detail‑Oriented
• Hematology
• Improvement Projects
• Innovation
• Intellectual Curiosity
• Laboratory Documentation
• Laboratory Informatics
• Laboratory Information Management System (LIMS)
• Medical Laboratories
• Microscopic Imaging
• Morphology
• Regulatory Compliance
• Regulatory Requirements
• Team Collaboration
• Technical Leadership
• Urinalysis

• None specified.

Salary range: $ – $. Eligible for annual bonus and long‑term incentive, if applicable. Benefits include medical, dental, vision, retirement (401(k)), paid holidays, vacation, and compassionate and sick days.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

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