Senior Scientist, Hybrid Modeler, Digital Insights, DSCS Digital Technologies

Location: West Point

** Job Description*
* ** Senior Scientist, Hybrid Modeler, Digital Insights, DSCS Digital Technologies*
* We are a global biopharmaceutical leader with a portfolio of prescription medicines, oncology, vaccines and animal health products. We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state-of-the-art laboratories, plants and offices that are designed to inspire our employees as we learn, develop and grow in our careers.  

We are proud of our over 125 years of service to humanity and continue to be one of the world's biggest investors in Research & Development.

We are seeking a  
** Senior Scientist
** to join our Digital Insights team within the Development Sciences and Clinical Supply (DSCS) Digital Technologies organization. Digital is the multiplier that will allow DSCS to deliver better experiments faster, efficient filing and launch, more robust supply chains and higher-confidence decisions across the portfolio.

The DSCS Digital Technologies organization is responsible for the invention and application of new digital tools/workflows to support scientists across drug substance development, drug product development and analytical development. We aspire to embed digital technologies into the fabric of DSCS culture to drive transformational impact. The tools that we develop are the teams developing them, and in this  
** Senior Scientist
** role, the successful candidate will advance the company's digital-first process development strategy by deploying mechanistic, CFD(Computational Fluid Dynamics)-based, and data-driven modeling approaches to design, de-risk, and optimize sterile drug substance (DS) and drug product (DP) manufacturing processes. The position will sit at the intersection of first-principles physics, advanced CFD, and machine learning / data science, enabling predictive understanding, robust scale-up, and accelerated clinical-to-commercial delivery across biologics and vaccines.

The successful candidate will play a technical leadership role in building and applying mixing and unit-operation virtual twins, integrating CFD with experimental data and AI/ML methods, and translating model outputs into actionable CMC and manufacturing decisions.

** _Responsibilities:_*
* + Develop and deploy a portfolio of mechanistic, CFD, and data-driven models to support development, scale-up, tech transfer, and manufacturing of sterile DS and DP processes across a biologics and vaccine pipeline.

+ Lead CFD-based mixing and unit operation modeling (e.g., compounding, dilution, pumping, filling, filtration) to quantify hydrodynamic stresses, energy dissipation rates, mixing times, and scale-up risk-enabling science-based operating windows and control strategies.

+ Integrate data science and machine learning with physics-based models to accelerate model execution, improve predictive accuracy, and enable rapid scenario screening.

+ Collaborate closely with stakeholders to de-risk sterile process scale-up, optimize formulation and process robustness, and support clinical‑to‑commercial transitions.

+ Design, execute, and interpret scale‑down and validation experiments to establish model credibility and scalability. Use experimental data to validate and refine CFD and ML models.

+ Own end-to-end modeling project execution, including problem formulation, data requirements, simulation workflows, model validation, reporting, and clear communication of predictions and uncertainty to cross‑functional stakeholders.

+ Establish best practices for modeling workflows, including pre/post‑processing, HPC and cloud computing utilization, data management, version control, and model reuse. Contribute to standardized playbooks and a central model repository.

+ Demonstrate excellent interpersonal, communication, and collaboration skills.

+ Embrace and model our core values including fostering a supportive culture where all can thrive.

+ Be able to effectively collaborate in a dynamic, integrated, and multidisciplinary team environment.

+ Demonstrate a clear ability to perform impactful scientific innovation in a…