Manufacturing Technician II; 2nd Shift

Business Introduction

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance. Our network of 37 manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024, helping to make a positive impact on the health of millions of people. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.

Lead and execute complex vaccine drug substance manufacturing operations while ensuring compliant, safe, and efficient production. Act as a technical expert in assigned processes, providing on‑floor leadership, training, problem‑solving support, and continuous improvement. Partner with supervisors and cross‑functional teams to ensure consistent execution of manufacturing activities.

• Execute complex drug substance manufacturing operations, including reagent and buffer preparation (weighing, formulation, pH adjustment/titration, filtration, aliquoting) in accordance with approved batch records and SOPs.
• Operate and monitor automated process equipment (chromatography, filtration systems, mixers, pumps, meters, scales), ensuring safe, efficient and compliant execution of manufacturing activities.

• Utilize advanced digital systems (electronic batch records, SCADA) to ensure data integrity, monitor process trends, identify deviations, support review by exception manufacturing and improve overall process outcomes.

• Adhere to GMP cleanroom requirements (Grade C/D/CNC gowning and flows) and perform or coordinate environmental monitoring, cleaning and sanitization activities per approved procedures.

• Troubleshoot equipment issues, respond to alarms, recognize early signs of equipment deterioration and escalate abnormal conditions in a timely manner.
• Document equipment status, abnormalities, and actions taken, and contribute to initiatives that improve equipment reliability and extend asset lifecycle.

• Ensure accurate, contemporaneous GMP documentation; participate in authoring and revising manufacturing and support SOPs; recognize and report deviations, support investigations, root‑cause analysis and CAPA development.

• Develop and deliver training materials, act as a qualified trainer, support onboarding and qualification of new team members and provide on‑floor process leadership.
• Assist supervisors with daily operations and lead manufacturing activities in the supervisor’s absence as required.

• Participate in troubleshooting and continuous improvement initiatives, applying GPS standards (5S, problem solving) to improve safety, quality, delivery and efficiency.

• Bachelor’s degree in biological sciences, chemistry, engineering, or a related technical field. Equivalent combinations of education and experience accepted; candidates without a degree may qualify with relevant GMP manufacturing experience (e.g., 3+ years in process operations, QC, or equipment maintenance) or professional certifications that show comparable technical depth.
• 1+ year of manufacturing or production experience.
• Experience in leadership in a GMP manufacturing environment.
• Experience in technical writing for GMP documentation (SOPs, MBRs, training materials) with working knowledge of GMP requirements.

• BS or BA in a biological or chemical science degree.
• Demonstrated experience authoring and maintaining technical documentation, including SOPs, work instructions and training materials in a regulated environment.
• Proven experience providing on‑floor leadership and technical guidance within a GMP manufacturing setting.
• Ability to safely handle acids, bases, oxidizers, chemicals and solvents in accordance with procedures and required PPE.
• Proficient in performing basic mathematical calculations (fractions, percentages, significant figures) and accurately measuring volume and weight.
• Demonstrated ability to follow detailed processing instructions…