Scientific Director, Discovery Pharmaceutics

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

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As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Pharmaceutical Product R&D

Job Category:
People Leader

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science‑based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

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We are searching for the best talent for a Scientific Director, Discovery Pharmaceutics to be located in Spring House, PA.

Purpose:

Global Discovery Pharmaceutics is part of the Pharmaceutical Development & Supply (PPDS) organization within the Discovery, Product Development and Supply (DPDS) division of Johnson & Johnson Innovative Medicine (JJIM). The group supports drug discovery programs from hit-to-lead through candidate selection, with a focus on the Synthetics Modalities portfolio — including small molecules, degraders, peptides, oligonucleotides, and conjugates.

As the Scientific Director
, you and your team will provide expert scientific leadership to enable informed molecule design and develop ability decisions. You will collaborate in close partnership with chemistry, biology, pharmacokinetics and pre-clinical safety.

As head of the team, you will provide scientific, strategic, and people leadership while driving the CMC deliverables for discovery programs. Your responsibilities include physical characterization, biopharmaceutical evaluation, and preclinical formulation support across diverse routes of administration - including oral, parenteral and intra-organ - and may include other advanced drug delivery strategies as required.

• Leading and developing a multidisciplinary scientific team
  , building technical depth, mentoring talent, fostering a culture of collaboration, innovation and continuous improvement.
• Developing
  innovative screening tools and formulation approaches
  , with the capability of meeting rapid cycle times and miniaturization, to influence and enable early discovery. Collaborating with academia and industry experts.
• Enhancing digital tools, data analytics and computational approaches to support develop ability assessments and improve the quality and speed of decision making in discovery programs.
• Enabling and overcoming exposure challenges for critical tool compounds or non-optimized leads with enabling formulations in support of PK, PK/PD, translational pharmacology and tolerability studies.
• Influencing compound design early to ensure lead candidates have the desired properties for specific drug delivery platforms and technologies to ensure patient convenience and compliance.
• Portfolio delivery and accelerating the transition from discovery to development through collaboration with key development functions to support the GLP toxicology studies, formulation strategy and dosage form design for clinical studies.
• Influencing risk management and mitigation
  .

• A PhD in Pharmaceutical Sciences, Chemistry, Chemical Engineering or a related field with 12+ years of relevant experience OR a Master's degree with 18+…