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VP Platform Chemistry

Job in Indiana, Indiana County, Pennsylvania, 15705, USA
Listing for: The Biopôle
Full Time position
Listed on 2026-02-04
Job specializations:
  • Research/Development
    Drug Discovery, Research Scientist, Biotechnology, Pharmaceutical Science/ Research
Salary/Wage Range or Industry Benchmark: 120000 - 160000 USD Yearly USD 120000.00 160000.00 YEAR
Job Description & How to Apply Below
Location: Indiana

Orbis Medicines is a pioneering biotech company powered by its automated nGen chemistry platform and a data‑driven approach. The company develops oral alternatives to injectable biologics, designing macrocycles with oral bioavailability through the combination of AI technologies, automated synthesis, and high‑throughput screening.

Orbis is seeking a VP Platform Chemistry to lead and continuously innovate its automated macrocycle synthesis platform. This role involves defining the strategic direction of the chemistry engine, driving platform innovation, and ensuring world‑class execution across discovery programs while being a key member of the R&D leadership team.

Key requirements
  • PhD in Chemistry, Pharmaceutical Sciences, or related field
  • 12+ years of industry experience in macrocycle or complex synthetic chemistry
  • Proven experience building automated or high‑throughput synthesis platforms
  • Strong understanding of macrocycle chemistry and DMTA‑driven discovery cycles
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