Research Technician

Department

BSD MED - Gastroenterology - Abadie Research Staff

We are a multidisciplinary team whose focus is to better understand how mucosal immune responses are dysregulated in the context of intestinal inflammatory disorders. We are particularly interested in characterizing adaptive immune responses that are deregulated in patients with celiac Disease. To get a better understanding of the role played by B and T lymphocytes in the context of Celiac Disease, we combine mouse and human studies to characterize those cells in health and disease and assess their function.

The Section of Gastroenterology is looking for a Research Technician interested in the field of mucosal immunology and Celiac Disease to work with the group of Dr. Abadie. Her group is working on a NIH‑funded projects aimed at deciphering the role of B lymphocytes in the context of celiac disease. These projects entail working with several complex mouse models that require high level skills in mouse colony handling, genotyping and organization, as well as processing samples obtained from celiac disease patients.

The candidate will be in charge of independently managing mouse colony breeding and genotyping. In addition, the candidate should have skills in molecular biology to perform the preparation of libraries for RNA‑sequencing and in cellular immunology to perform and assist with immunology experiments that involve cell isolation, cytokine‑based assays, and flow cytometry. Finally, the candidate will participate in laboratory meetings regarding current research and other lab activities and will assist with organizing laboratory and ordering supplies.

• Management of mouse colonies breeding and genotyping.
• Isolate and freeze cells from peripheral blood mononuclear cells and intestinal biopsies.
• Perform RNA isolation, and library preparation for RNA sequencing.
• Perform flow cytometry experiments and Elisa.
• Perform and assist with immunology experiments under supervision of principal investigator, postdoctoral researcher or graduate student.
• Participate in laboratory meetings regarding current research and other lab activities.
• Assist with organizing laboratory and ordering supplies.
• Maintains a safe environment for others and self; adheres to safety policies and procedures.
• Maintains technical and administrative support for a research project.
• Analyzes and maintains data and/or specimens. Conducts literature reviews. Assists with preparation of reports, manuscripts and other documents.
• Performs other related work as needed.

Education: Minimum requirements include a college or university degree in related field.

Work Experience: Minimum requirements include knowledge and skills developed through < 2 years of work experience in a related job discipline.

Certifications: ---

Education:

• Bachelor's degree in molecular biology, biochemistry, or cell culture.

Experience:

• Experience in molecular biology and genomics.

Technical Skills or Knowledge:

• Basic immunology coursework.
• Skill in mouse breeding and genotype analysis.

• Analytical skills.
• Problem‑solving skills.
• Attention to detail.
• Organizational skills.
• Verbal and written communication skills.
• Work independently and as part of a team.

• Resume/CV (required)
• Cover Letter (required)

When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.

Research

Individual Contributor

40

No

No

No

Salary

Exempt

$50,000.00 - $70,000.00

The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.

Yes

The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.

The University of Chicago…