Senior Scientist, Biology-Discovery

Overview

We’re seeking an experienced Senior Scientist to join the Infectious Disease and Vaccines department at our research site in West Point, PA. The candidate will play an essential role in a team responsible for the discovery and development of novel antiviral treatments.

• Design and independently execute experiments to interrogate virus biology, virus‑host interactions, and immunological responses using biochemical and cell‑based assays.
• Develop and optimize mammalian cell culture, cell‑based antiviral assays, RT‑qPCR/qPCR, protein analysis, and virology fundamental assays.
• Ensure accurate record‑keeping, adherence to biosafety procedures, and reproducible experimental workflows.

• Education: BS/BA in Biology or Biomedical Sciences with a minimum of 7 years of experience, or MS degree with 4 years, or PhD with more than 1 year of postdoctoral experience.
• Experience & Knowledge: Strong background in virology, immunoassays, genomic technologies, cell biology, animal pharmacology, and general understanding of infectious disease drug development.
• Demonstrated creativity, teamwork, and independent analytical problem‑solving skills.

• Mammalian cell culture – maintenance and manipulation of immortalized cell lines and primary cells.
• Cell‑based antiviral assays – design, execution, and analysis of infection and drug‑response assays.
• RT‑qPCR/qPCR and nucleic acid extraction – robust RNA/DNA isolation and quantitative PCR for viral load and gene expression.
• Protein analysis – Western blotting and basic protein quantitation.
• Virology fundamentals – safe handling, propagation, and titration of viruses (plaque/titer or focus‑forming assays).
• Awareness of emerging biology and new technologies.
• Good laboratory practices and documentation – accurate record‑keeping, adherence to biosafety procedures, and reproducible experimental workflows.

• High‑content or fluorescence microscopy – image acquisition and basic image analysis for phenotypic readouts.
• Data analysis and statistics – ability to analyze dose–response, kinetics, and experimental data using tools such as R or Python.

• Salary range: $ – $ (based on education, qualifications, experience, and geographic location).
• Eligibility for annual bonus and long‑term incentive (if applicable).
• Benefits: medical, dental, vision, retirement (401(k)), paid holidays, vacation, compassionate and sick days.
• Equal Employment Opportunity:
  We provide equal opportunities to all employees and applicants and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics.
• US and Puerto Rico residents only.
• San Francisco residents: consideration in compliance with the San Francisco Fair Chance Ordinance.
• Los Angeles residents: consideration in compliance with the City of Los Angeles Fair Chance Initiative.
• Job posting end date: 06/17/2026.
• Requisition : R400544.