Associate Principal Scientist, Biology-Discovery

Overview

We are committed to improving the health and well‑being of people around the world. As a leading global pharmaceutical company, we strive to make a difference through innovative research, discovery, and development of life‑saving medications and vaccines. Join our team as an Associate Principal Scientist in the Quantitative Biosciences team in West Point, PA, to lead antiviral assay development and drive novel therapies in HIV‑1 and other infectious diseases.

• Develop and execute cell‑based antiviral assays, critically analyze data, and integrate findings with other functional areas to advance infectious disease discovery programs.
• Represent Quantitative Biosciences on core discovery program teams and partner across matrixed program teams to define strategy, goals, and coordinate engagement.
• Collaborate with biology, chemistry, and screening colleagues to identify next‑generation drug targets.
• Identify, validate, and integrate new technologies or methodologies to increase efficiency and productivity, drive program progression, and facilitate clinical translation.
• Provide guidance and mentorship to less experienced scientists, fostering their professional development.
• Work with automation engineers to transfer bench‑developed assays onto integrated robotic systems.
• Properly document protocols and findings, author preclinical regulatory documents, and comply with all laboratory safety requirements.
• Integrate and interpret complex data and communicate science and strategy to stakeholders and management.

An advanced degree in molecular virology, pharmacology, or a related discipline, and a BS degree with 12+ years relevant experience, or an MS degree with 8+ years relevant experience, or a Ph.D. with 3+ years relevant experience. Proficiency in HIV‑1 biology, including pathogenesis, resistance, and/or latency. Highly skilled in virology with expertise in a range of virological, molecular and cellular techniques, including in vitro and in vivo disease models.

Proven track record in designing and executing cell‑based antiviral assays using detection technologies such as fluorescence imaging, luminescence, flow cytometry, Mesoscale/Luminex. Superb time‑management skills with the ability to balance competing priorities and execute multiple tasks concurrently. Robust understanding of drug discovery and clinical development from lead identification through preclinical candidate delivery. Ability to thrive in a highly matrixed work environment and communicate effectively with a broad range of stakeholders.

Passion for innovation and strong analytical problem‑solving capabilities. Excellent written and oral communication skills. Experience using automated liquid handlers for assay development. Ability to adapt to changing priorities.

• Assay Development
• Biochemical Assays
• Biochemistry
• Bioinformatics
• Cell Biology
• Cytometry
• Drug Discovery Process
• Ethical Compliance
• High‑Throughput Screening
• Immunology
• Infectious Disease
• Laboratory Automation
• Laboratory Safety
• Mammalian Cell Culture
• Molecular Biology
• Pharmacodynamics
• Pharmacokinetics
• Pharmacotherapeutics
• Strategic Thinking
• Teamwork
• Virology

• None specified

• Location:
  
  West Point, PA
• Employee Status:
  Regular
• Relocation:
  Domestic
• VISA Sponsorship:
  Yes
• Travel Requirements:
  No
• US and Puerto Rico Residents Only

Salary range: $ – $. Eligible for annual bonus and long‑term incentive, if applicable.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC, Know Your Rights, EEOC GINA Supplement. We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills and backgrounds.