Associate Principal Scientist, Discovery Analytical Research

Associate Principal Scientist

The Discovery Analytical Research group in West Point, Pennsylvania is seeking an Associate Principal Scientist position to drive innovation in analytical measurement technologies, enabling the discovery of new drug candidates across various modalities. Key deliverables will include the development, implementation, and execution of analytical measurement technologies that accelerate the pace of discovery research and influence molecular design. The successful candidate must be able to collaborate in a dynamic, integrated, and multidisciplinary team environment.

The primary role of the successful candidate will be to lead the development and application of advanced analytical and biophysical characterization strategies for our early-stage vaccines pipeline, playing a critical role in influencing molecular design, candidate selection, and manufacturability through data-driven insights and the deployment of novel technologies.

Primary Responsibilities:

• Represent the discovery analytical research group in project teams, provide technical guidance, and drive scientific strategy.
• Develop, implement, and troubleshoot advanced analytical methods, primarily separation-based techniques and biophysical techniques utilizing automation.
• Solve complex problems and drive innovation in analytical measurement technologies.
• Collaborate in multidisciplinary teams, foster partnerships with discovery groups, and contribute to organizational goals.
• Mentor and develop junior scientists and promote a culture of learning and innovation.
• Ensure high standards of data integrity and documentation.
• The successful candidate must be able to effectively collaborate in a fast-paced, integrated, multidisciplinary team environment.

Education

Minimum Requirements:

• Ph.D. in Analytical Chemistry or related field with 4+ years of biopharmaceutical industry experience.

Required

Experience and Skills:

• Deep expertise in separation techniques (UPLC, LC-CAD, CE-SDS, SEC, BCA, Western) for vaccines.
• Strong experience in biophysical techniques (e.g. DLS, SLS, MFI, DSC, SAXS) for vaccines.
• Experience with automation workflows, including liquid handling platforms (e.g., Tecan, Bravo, NIMBUS)
• Demonstrated scientific ability through publications in peer reviewed journals and presentations in scientific conferences.
• Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills.
• Ability to deliver complex objectives under challenging timelines in a rapidly changing environment.
• Ability to work in a team environment with cross-functional interactions.

Preferred

Experience and Skills:

• Experience with electronic laboratory notebook applications and good documentation practices.
• Familiarity with coding/scripting (e.g., Python, R) for automation or data analysis

Why Join Us?

Be part of a dynamic, innovative team. Lead impactful research and contribute to drug discovery. Opportunities for professional growth and publication.

Required Skills:

Adaptability, Analytical Chemistry, Analytical Method Development, Assay Development, Automation, Biological Assay Development, Biopharmaceutical Industry, Biopharmaceuticals, Biopharmaceutics, Cell-Based Assays, Chromatographic Techniques, Cross-Functional Teamwork, Drug Discovery Process, External Collaboration, Foster Innovation, High Resolution Mass Spectrometry (HRMS), Laboratory Documentation, Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry Analysis, Multidisciplinary Collaboration, Optimism, Pharmaceutical Biology, Process Analytical Technology (PAT), Protein Analysis

Preferred

Skills:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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