Sr. Scientist Onc

Job Description

Position:
Sr. Scientist, Oncology (Prostate Cancer).

Location:

Spring House, Pennsylvania, United States.

The Sr. Scientist will join a drug discovery team developing transformative therapies for the treatment of prostate cancer. They will make key contributions, both in the lab and strategically, that drive the advancement of multiple preclinical projects in a fast‑paced environment.

• Independently design and execute cellular and molecular in vitro pharmacology experiments; analyze data and present results at project team and governance meetings.
• Develop novel assays and in vitro models supporting therapeutic development projects and the Prostate Discovery team.
• Support the generation of comprehensive and well‑designed preclinical data packages in support of various programs, including IND readiness for First‑In‑Human (FIH) studies.
• Identify novel prostate cancer targets utilizing LLM AI, –omics datasets, and the academic literature.

• Education:
  
  MS with at least 10 years of relevant industry experience, or BS with at least 15 years of relevant industry experience (or equivalent training/experience) performing progressively advanced duties at the Scientist level.
• Proficient in multiple cell and molecular biology assays: flow cytometry, Western blot, RT‑PCR, MSD/ELISA, immunofluorescence, cytotoxicity/proliferation assays (Cell Titer‑Glo and Incucyte‑based).
• Experienced in basic and advanced tissue culture models such as patient‑derived organoids, spheroids, and immune cells. Analysis of ex vivo patient samples by flow cytometry and other techniques.
• Demonstrated ability to effectively collaborate in cross‑functional team environments. Excellent oral and written communication skills. Able to present scientific data and concepts to diverse audiences.
• Experience in prostate cancer research and/or drug development.
• Experienced in generating over expressing (lipid transfection and lentiviral transduction) and knockout (CRISPR Cas9) cell lines.
• Familiarity with Flow Jo, Graph Pad Prism, Mosaic, Genedata Biologics and Revvity Signals Electronic Notebook.
• Demonstration of creativity and novel approaches to solving scientific problems.

• Accelerating
• Analytical Reasoning
• Clinical Data Management
• Critical Thinking
• Data Analysis
• Data Reporting
• Data Savvy
• Design of Experiments (DOE)
• Drug Discovery Development
• Issue Escalation
• Molecular Diagnostics
• Pharmaceutical Microbiology
• Product Knowledge
• Research Proposals
• Scientific Research
• Standard Operating Procedure (SOP)
• Technologically Savvy

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs.

If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via  Internal employees can contact AskGS to be directed to your accommodation resource.