Associate Principal Scientist, Discovery Analytical Research

Job Description

The Discovery Analytical Research group in West Point, Pennsylvania is seeking an Associate Principal Scientist to drive innovation in analytical measurement technologies, enabling the discovery of new drug candidates across various modalities. Key deliverables include the development, implementation, and execution of analytical measurement technologies that accelerate the pace of discovery research and influence molecular design.

The successful candidate will lead the development and application of advanced analytical and biophysical characterization strategies for our early‑stage vaccines pipeline, influencing molecular design, candidate selection, and manufacturability through data‑driven insights and deployment of novel technologies.

• Represent the discovery analytical research group in project teams, provide technical guidance, and drive scientific strategy.
• Develop, implement, and troubleshoot advanced analytical methods, primarily separation‑based and biophysical techniques utilizing automation.
• Solve complex problems and drive innovation in analytical measurement technologies.
• Collaborate in multidisciplinary teams, foster partnerships with discovery groups, and contribute to organizational goals.
• Mentor and develop junior scientists and promote a culture of learning and innovation.
• Ensure high standards of data integrity and documentation.
• Effectively collaborate in a fast‑paced, integrated, multidisciplinary team environment.

Ph.D. in Analytical Chemistry or related field with 4+ years of biopharmaceutical industry experience.

• Deep expertise in separation techniques (UPLC, LC‑CAD, CE‑SDS, SEC, BCA, Western) for vaccines.
• Strong experience in biophysical techniques (DLS, SLS, MFI, DSC, SAXS) for vaccines.
• Experience with automation workflows, including liquid handling platforms (Tecan, Bravo, NIMBUS).
• Demonstrated scientific ability through publications in peer‑reviewed journals and presentations at scientific conferences.
• Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills.
• Ability to deliver complex objectives under challenging timelines in a rapidly changing environment.
• Ability to work in a team environment with cross‑functional interactions.

• Experience with electronic laboratory notebook applications and good documentation practices.
• Familiarity with coding/scripting (Python, R) for automation or data analysis.

Be part of a dynamic, innovative team. Lead impactful research and contribute to drug discovery. Opportunities for professional growth and publication.

$142,400 – $224,100 per annum.

We offer a comprehensive package of benefits including medical, dental, vision, and other healthcare insurance; retirement benefits with 401(k); paid holidays and vacation; sick and compassionate leave. Detailed information is available on our website.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. We comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit EEOC and the GINA Supplement.