Scientist, Research Scientist

Scientist

Looking for Personalized Medicine and Translational Science Expert, for a temporary contract position accountable for executing Personalized and Predictive Medicine (PPM) strategies, serving as the point person for scientific advice on portfolio compounds.

Will work collaboratively with interfaces across the entire company to effectively deliver PPM value to the drug discovery and development process.

The successful candidate will lead studies to evaluate genomic and other biomarkers for association with drug response and safety, as well as lead genomic characterization of drugs' mode of action and toxic genomics.

Integrating PPM activities effectively in the assigned clinical development programs in collaboration with all relevant functions.

Advising R&D functions as an expert in all PPM-related aspects of scientific principles, clinical protocol development, regulatory guidance, intellectual property (IP), assay development, commercial value, etc.

Executing Pharmacogenomics and biomarker studies, drafting relevant documentation and being accountable for its on-time execution

Ensuring selection of cost-effective and appropriately validated assays; manage vendors in experimental set-up and implementation in clinical trials

Collaboratively developing the statistical analysis plan (SAP), or equivalent, for PPM projects within and parallel to the relevant clinical development program

Proactively identify challenges and develop contingency plans as appropriate

Participation in PPM and clinical development team meetings

PhD/MS in human genetics, genomics, molecular biology, computational biology, similar

2+ years' experience in pharmacogenomics and/or biomarker applied research, preferably in the pharmaceutical setting

Knowledgeable in the field of genetics, bioinformatics and statistical analysis and interpretation of multivariate Pharmacogenomics and/or biomarker data