Senior Director, Neuroimmunology Research

Johnson & Johnson (J&J) is seeking an accomplished scientific leader to join our R&D organization as Senior Director, Neuroimmunology Research, reporting to the VP of Global Discovery and External Innovation for Neuroscience, to be located in Spring House, PA;
San Diego, CA; or Cambridge, MA.

Our Neuroscience team tackles the world’s toughest brain health challenges including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, myasthenia gravis, epilepsy, major depressive disorder, bipolar disorder, schizophrenia, and autism.

Job Function:
Discovery & Pre‑Clinical/Clinical Development
Job Sub‑Function:
Clinical Development & Research – Non‑MD
Job Category:
Scientific/Technology
Locations:
Cambridge, Massachusetts;
San Diego, California;
Spring House, Pennsylvania

• Develop and lead scientific strategy at the interface of immunology and neuroscience, contributing to the overall TA strategy, with a focus on novel therapies for neurological disorders.
• Provide deep subject‑matter expertise in regulatory T cell (Treg) biology and immune tolerance, B cell biology, antibody‑mediated disease, deep B cell depletion approaches, autoimmunity, neuroinflammation, and CNS immune mechanisms.
• Identify opportunities to apply immune‑modulating approaches to diseases such as Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, and autoimmune psychosis.
• Build and strengthen cross‑functional collaboration between J&J’s Neuroscience and Immunology Discovery teams.
• Support the VP of Early Development in shaping the translational strategy to move assets to the clinic.
• Present projects and strategy at governance meetings.
• Lead target identification, validation, translational strategy, biomarker development, and portfolio prioritization in neuroimmunology programs.
• Guide internal and external research collaborations with academic institutions, biotech partners, and key opinion leaders.
• Represent the company externally through scientific conferences, advisory boards, and publications.
• Drive scientific excellence and ensure programs are informed by cutting‑edge external science and competitive intelligence.
• Support external collaborations and diligences on licensing and M&A opportunities.

• PhD, or MD/PhD in Immunology or Neuroscience.
• 10+ years of relevant industry and/or academic experience, with significant leadership experience in drug discovery or translational research.
• Deep expertise in relevant immune‑science (Treg biology, immune tolerance mechanisms, and/or B cell depletion strategies).
• Strong understanding of the role of the immune system in neurological diseases.
• Experience translating biological insights into therapeutic hypotheses and development programs.
• Demonstrated success leading matrixed, multidisciplinary teams.
• Strong publication record in high‑impact peer‑reviewed journals.
• Excellent communication, influencing, and executive presence.

• Base pay range: $196,000 – $342,700 per year.
• Retirement participation in the company’s 401(k) plan.
• Vacation: 120 hours per calendar year.
• Sick time: 40 hours per calendar year (48 in Colorado, 56 in Washington).
• Holiday pay, including floating holidays: 13 days per calendar year.
• Work, personal, and family time: up to 40 hours per calendar year.
• Parental leave: 480 hours within one year of birth/adoption/foster care.
• Bereavement leave: 240 hours for immediate family member; 40 hours for extended family member per year.
• Caregiver leave: 80 hours in a 52‑week rolling period.
• Volunteer leave: 32 hours per calendar year.
• Military spouse time‑off: 80 hours per calendar year.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. Johnson & Johnson actively seeks qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via  or contact AskGS to be directed to your accommodation resource.