Distinguished Scientist, Biologics Discovery

Responsibilities

• Serve as the scientific and strategic leader between Therapeutic Discovery & Supply (TDS) and Discovery teams
• Enable seamless end‑to‑end decision‑making for biologics programs and technical platforms
• Identify and mitigate development risks during the discovery phase
• Ensure that structural, biophysical, expression, and develop ability insights are effectively integrated into CMC strategies and program planning
• Identify early opportunities to assess knowledge gaps to derisk program development
• Lead platform alignment efforts to ensure data and decisions are translatable across discovery and development
• Provide deep scientific guidance on molecule selection, engineering, develop ability, manufacturability, expression, and protein structure–function considerations
• Build trusted cross‑functional partnerships and influencing decision‑making across Therapeutics Discovery (TD), Preclinical Sciences & Translational Safety (PSTS), Therapeutic Areas (TAs), and TDS

• PhD in Structural Biology, Biochemistry, Biophysics Chemical or Biomedical Engineering, or a closely related field
• A minimum of 15 years of biopharmaceutical R&D experience spanning both Discovery and Development / CMC functions
• Deep technical expertise in protein structure, develop ability principles, and expression considerations
• Strong understanding of end‑to‑end biologics development including scientific and operational needs of CMC
• Proven ability to shape and implement large cross‑functional projects in a matrixed environment
• Excellent communication, interpersonal, and scientific storytelling skills
• Experience supporting IND‑enabling or early clinical development efforts preferred
• Familiarity with predictive modeling, sequence/structure analysis tools, or computational develop ability platforms preferred