Principal Scientist, Biostatistics

Job Title:

Principal Scientist, Biostatistics

Employer:

Janssen Research & Development, LLC

Job Code: A011.4898

Location:

Spring House, PA, United States

Job Type: Full-Time

Posting will close on 8/30/2026.

• Support statistical aspects of business-critical and regulatory commitments of clinical trials to develop new drug to treat patients with moderate/severe Rheumatoid or Psoriatic Arthritis.
• Apply high quality statistical methodology in assigned projects of the disease/scientific/functional area and ensure health authority acceptability for pharmaceutical research and development strategies and execution.
• Execute individual project responsibilities, including meetings with necessary project team members, reporting activities, exploratory analyses/graphics, and additional analyses to support publications for individual clinical trials/studies/projects.
• Ensure that documents, specifications, programs, and macros are consistent and comply with project and company standards.
• Follow best practices for Data Integrity.
• Take a lead in providing SDS support to experimental design, modeling, analysis planning, analysis execution, interpretation, and statistical communications.
• Provide input to the team in terms of optimizing study or trial designs in line with study or indication level objectives.
• Suggest and perform the evaluation of alternative or innovative approaches to statistical methods or business processes.
• Participate as a member of professional organizations, such as attending meetings as chair or presenter.
• Supervise contractors, special assignment personnel, interns, and/or co-ops as required.
• Mentor junior colleagues in techniques, processes, and responsibilities.
• Proactively identify complexity in terms of Scientific, Statistical, Health Authority, Operational, and Partnership issues.
• Collaborate and consult with non-statisticians, translating complex statistical concepts for drug research and development partners.
• Participate in process improvement or standards development initiatives.
• Leverage SAS or R, as well as other relevant computational tools as required.
• May telecommute per company's policies (hybrid).

• Ph.D. degree in Statistics or a related field.
• 3 years of experience in a Principal Scientist, Biostatistics-related occupation or the job offered.
• Strong proficiency with SAS or R and other relevant computational tools.
• Experience supporting business-critical and regulatory commitments of clinical trials.
• Ability to work in a collaborative team environment and communicate complex statistical concepts effectively.
• Demonstrated ability to lead statistical design, analysis planning, execution, interpretation, and statistical communications.

• Vacation – 120 hours per calendar year
• Sick time – 40 hours per calendar year (48 hours for employees residing in Colorado, 56 hours for employees residing in Washington)
• Holiday pay, including Floating Holidays – 13 days per calendar year
• Work, Personal and Family Time – up to 40 hours per calendar year
• Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
• Caregiver Leave – 80 hours in a 52-week rolling period
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year
• Eligible for participation in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
• Eligible for the Company’s long-term incentive program.
• Eligible for medical, dental, vision, and other benefits as provided for in the applicable Collective Bargaining Agreement.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law.

We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via  or contact AskGS to be directed to your accommodation resource.