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Senior Scientist, In-Silico Formulations

Job in Malvern, Chester County, Pennsylvania, 19355, USA
Listing for: J&J Family of Companies
Full Time position
Listed on 2026-07-31
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery
Job Description & How to Apply Below
Location: Malvern

Senior Scientist, In-Silico Formulations

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Biotherapeutics R&D

Job Category:
Scientific/Technology

Location:

Malvern, Pennsylvania, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for Senior Scientist, In-Silico Formulations, located in Malvern, PA.

Purpose:

The Senior Scientist, In-Silico Formulations will work in the Protein Drug Product Development & Delivery (DPD&D) department. This role requires expertise in computational biophysics, protein computational modeling, and/or formulation science. In this role the candidate will be responsible for applying computational methods, including antibody homology modeling, molecular dynamics, intrinsic property calculations, and artificial intelligence/machine learning (AI/ML) to guide formulation selection and optimization.

Additionally, the candidate will advance various drug development projects, participate in multi-disciplinary teams including biologists, chemical engineers, pharmacists, and structural biologists, and provide key expertise in the use and interpretation of structural data related to drug development.

You will be responsible for:

  • Execution of sophisticated experiments using advanced computational techniques on local workstations and/or remote servers.
  • Clearly communicating the results of computational experiments to team members facilitating the formulation selection/optimization of new antibodies.
  • Developing novel computational methods to address key drug development questions.
  • Qualifications / Requirements:

    Education:

    • A minimum of a Ph.D. in chemical engineering, computational sciences, bioengineering, chemistry, biophysics, or related subject area OR master's degree with at least 3 years of related experience OR bachelor's degree with at least 6 years of related experience

    Experience and

    Skills Required:

    • Expertise using molecular dynamics packages (e.g., GROMACS, NAMD, Amber, CHARMM), modeling/visualization tools (e.g., MOE, Schrodinger, VMD, PyMOL), and data analysis/automation methods (e.g., shell scripting and Python) is preferred.
    • Demonstrated ability to model and simulate diverse modalities (e.g., small molecules, proteins, lipids, DNA/RNA, etc.)
    • Excellent writing and verbal skills

    Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

    Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via careers contact information, internal employees contact AskGS to be directed to your accommodation resource.

    Position Requirements
    10+ Years work experience
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