Director, Translational Medicine Clinical Lead-Immunology

Director, Translational Medicine Clinical Lead, Translational Science & Medicine

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

We are searching for the best talent for a Director, Translational Medicine Clinical Lead, Translational Science & Medicine to be in Spring House, PA, La Jolla, CA or Cambridge, MA.

The Director, Translational Medicine (TM), will be a program and experimental medicine leader in the Immunology Translational Science and Medicine (TSM) function. In this position, the Director, TM, will decisively contribute to accelerating the Immunology pipeline from portfolio entry to Proof-of-Concept (PoC).

The Director, TM, will function as a clinical lead/study responsible physician on early development programs and trials. They will contribute to creating translational plans for programs that are aligned with overall TA strategy and with relevant disease area and/or pathway strategies. They will be empowered to lead a cross-functional clinical trial team to deliver on the trial's major execution milestones within governance-approved timeline and budget commitments.

This responsibility extends end to end for clinical trials: from initial protocol design to continued monitoring and problem solving on trial execution to the analysis, interpretation, and communication of study results. This role will partner with Translational Sciences, and deep engagement with investigators and external experts is expected. In this leadership role, they will be supported by the senior leaders within the Translational Science and Medicine function, including the relevant disease area leaders (both in clinical development and biomarker science) and a clinical study responsible scientist.

The span of studies in scope are phase 1 (including focused experimental medicine studies) through Proof of Concept.

Responsibilities are as follows:

• Design and execute program translational strategies integrating both disease and pathway approaches.
• Design and execute early clinical trials through PoC including experimental medicine studies.
• Lead a cross-functional trial team to deliver on study milestones and commitments.
• Collaborate with translational science on the development and implementation of clinical biomarker and patient segmentation strategies.
• Support experimental medicine studies.
• Support Business Development, including due diligence activities.
• Represent TM on early development teams.
• Represent TM for project teams when presenting to portfolio, project, and governance meetings.
• Lead or participate in cross-functional working groups such as scientific and safety review boards.
• Identify and collaborate with academic translational sites to optimize the translational strategy and plans for programs.
• Prepare and/or direct the preparation and review of protocols, clinical study reports and translational medicine sections of Translational plans, IBs, INDs, abstracts, manuscripts, and technical reports.
• Responsible for presentation of results and updates of projects at department, project, corporate and scientific meetings.

Qualifications:

• MD or MD/PhD degree required.
• Minimum of 3 years of industry and/or translational research experience required.
• Demonstrated supervisory and/or leadership experience with clinical and/or research teams is required.
• Training in Immunology and early clinical development trials is strongly preferred.
• Experience with innovative immune cell-based or biologic therapies is preferred.
• Strong track record in publications is preferred.
• Willingness and ability to travel, including trans-Atlantic travel (up to ~10%) is required.
• Location is Spring House, PA, Cambridge, MA or La Jolla, CA.

Subject to the terms of their respective plans, employees are eligible to…