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Experienced Scientist, In-vivo CAR-T

Job in Spring House, Montgomery County, Pennsylvania, 19477, USA
Listing for: Johnson & Johnson Innovative Medicine
Full Time position
Listed on 2026-08-17
Job specializations:
  • Research/Development
    Pharmaceutical Science/ Research, Research Scientist, Biotech Research, Regulatory Compliance Specialist
Salary/Wage Range or Industry Benchmark: 95000 - 150000 USD Yearly USD 95000.00 150000.00 YEAR
Job Description & How to Apply Below
Location: Spring House

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

Learn more at

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biotherapeutics R&D

Job Category

Scientific/Technology

All Job Posting Locations

Leiden, Netherlands, Spring House, Pennsylvania, United States of America

Job Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands.

Purpose

The Experienced Scientist will support the formulation development, optimization, and scale-up of lentiviral vector (LVV) drug product formulation early to late-stage development. The role combines hands‑on laboratory work with strong cross‑functional collaboration to ensure robust, scalable, and GMP‑ready processes.

Key Responsibilities
  • Formulation development and optimization of viral vectors e.g., LVV drug product across early and late development stages
  • Perform hands‑on laboratory work including formulation design, optimization, and characterization
  • Analyze and interpret data to support formulation development, optimization, and decision‑making
  • Support formulation robustness activities
  • Contribute to scale‑up and manufacturing readiness, including support of technology transfer to internal sites or CMOs
  • Collaborate cross‑functionally with Analytical Development, Statistical, API, MSAT, Quality, Manufacturing, and Regulatory teams to ensure alignment on formulation strategy and execution of viral vectors
  • Document experimental work and results in accordance with GxP and data integrity requirements
  • Participate in troubleshooting activities and continuous process improvement initiatives
Qualifications Required
  • B.S. or M.S. with 2-4 years of experience in an appropriate scientific discipline (Life Sciences or Chemical Engineering) is required
  • Relevant experience in formulation development of viral vectors and/or advance therapies
  • Strong hands‑on laboratory experience in drug product development of viral vector development and statistics
  • Understanding of process scale‑up, technology transfer, and GxP principles
  • Strong scientific problem‑solving and data interpretation skills
  • Hands‑on, proactive, and detail‑oriented approach
  • Ability to work effectively in a cross‑functional, matrixed environment
  • Clear and concise communication skills (written and verbal)
  • Ability to manage multiple priorities in a dynamic development environment
Preferred
  • Experience with viral vector platforms, LVV in particular, and/or advanced therapies
  • Familiarity with formulation implementation for both early and late‑stage development, process validation (e.g.,…
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