Distinguished Scientist, Biologics Discovery Process Research Integrator

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Discovery & Pre-Clinical/Clinical Development

Biotherapeutics R&D

Scientific/Technology

Malvern, Pennsylvania, United States of America, Spring House, Pennsylvania, United States of America

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

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We are searching for the best talent for a Distinguished Scientist, Biologics Discovery Process Research (BDPR) Integrator to be located in Spring House, PA or Malvern, PA.

The Distinguished Scientist, BDPR Integrator will serve as the scientific and strategic leader between Therapeutic Discovery & Supply (TDS) and Discovery teams, enabling seamless end-to-end decision-making for biologics programs and technical platforms. This role is deeply technical and focuses on proactively identifying and mitigating development risks during the discovery phase. The leader will ensure that structural, biophysical, expression, and develop ability insights are assessed and effectively integrated into Chemistry, Manufacturing and Controls (CMC) strategies and program planning.

Additionally, the leader will be tasked with identifying early opportunities to assess knowledge gaps to derisk program development.

They will be responsible for leading platform alignment efforts to ensure data and decisions are translatable across discovery and development and build out knowledge management and sharing systems to integrate knowledge across the teams.

• Leading cross-functional teams to deliver on technical and strategic projects with the focus on ensuring speed to clinic and full translation of data and decisions.
• Building a robust business process to enable continuous learning cycles and knowledge sharing across technical teams in Discovery, Product Development & Supply (DPDS).
• Serving as the TDS BDPR integrator on complex Discovery project teams, aligning strategy, data expectations, and technical risk assessment across Discovery and Development.
• Providing deep scientific guidance on molecule selection, engineering, develop ability, manufacturability, expression, and protein structure-function considerations.
• Identifying and mitigating CMC, technical, operational, and manufacturability risks early, translating findings into clear program recommendations and mitigation plans.
• Ensuring continuity of scientific rationale and technical context as programs advance from Discovery through candidate nomination and IND-enabling activities.
• Building trusted cross-functional partnerships and influencing decision-making across Therapeutics Discovery (TD), Preclinical Sciences & Translational Safety (PSTS), Therapeutic Areas (TAs), and TDS in matrixed governance and technical forums.

• PhD in Structural Biology, Biochemistry, Biophysics Chemical or Biomedical Engineering, or a closely related field is required.

• A minimum of 15 years of biopharmaceutical R&D experience spanning both Discovery and…