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Scientist, Pharmacokinetics

Job in West Point, Montgomery County, Pennsylvania, 19486, USA
Listing for: Merck
Full Time position
Listed on 2026-09-05
Job specializations:
  • Research/Development
    Pharmaceutical Science/ Research, Research Scientist, Biotech Research
Salary/Wage Range or Industry Benchmark: 87300 USD Yearly USD 87300.00 YEAR
Job Description & How to Apply Below
Location: West Point

Scientist, Drug Metabolism And Pharmacokinetics

We are seeking a motivated Scientist to join the Drug Metabolism and Pharmacokinetics (DMPK) group within the Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) organization at our Research & Development Division in West Point, PA.

The primary responsibility of this role is to support drug discovery and development programs through the execution of in vitro ADME/DMPK assays and generation of high-quality quantitative bioanalytical data. The successful candidate will work under guidance to conduct experiments that characterize drug metabolism and disposition with a strong emphasis on LC-MS–based bioanalysis and contribute data to inform project decisions.

This position is primarily laboratory-based and emphasizes technical rigor, reproducibility, and data quality. The candidate will collaborate closely with multidisciplinary teams and contribute to assay execution, troubleshooting, and workflow optimization, including the application of LC-MS technologies and emerging automation tools. The ideal candidate is detail-oriented, proactive, and eager to develop expertise in DMPK sciences within a collaborative and fast-paced research environment.

Position

Qualifications:

Education Minimum Requirement

Bachelor's degree with 1–3 years of relevant experience, or Master's degree with 0–2 years of relevant experience in analytical chemistry, biochemistry, pharmaceutical sciences, or a related discipline

Required Experience and Skills

  • Strong foundation in analytical chemistry, biochemistry, or related field
  • Hands-on experience with LC-MS/MS for quantitative bioanalysis of small molecules or biologics including sample preparation, method execution, and data acquisition
  • Familiarity with analysis of biological matrices (e.g., plasma, tissues, enzymes, cell systems)
  • Proficiency in data analysis tools (e.g., Excel, Graph Pad Prism, electronic laboratory notebooks)
  • Strong attention to detail and commitment to generating high-quality, reproducible data
  • Ability to follow established protocols and troubleshoot routine experimental or instrumentation issues
  • Effective communication and collaboration skills in a team-based environment
  • Demonstrated problem-solving ability, learning agility, and growth mindset

Preferred Experience and Skills

  • Experience with in vitro ADME/DMPK assays (e.g., metabolic stability, protein binding, reaction phenotyping, enzyme inhibition)
  • Working knowledge of LC-MS instrumentation, including basic troubleshooting, maintenance, or method optimization
  • Experience with cell-based assays or tissue/subcellular systems
  • Familiarity with laboratory automation, liquid handling systems, or high-throughput workflows
  • Experience leveraging data visualization tools (e.g., Spotfire)
  • Prior experience in a pharmaceutical, biotech, or contract research organization

Required Skills:

Analytical Chemistry, Bioanalysis, Biochemistry, Biopharmaceuticals, Biopharmaceutics, Cell Culture Techniques, Data Analysis, Data Visualization, Detail-Oriented, Drug Metabolism, Ethical Compliance, Good Laboratory Practices (GLPs), Immunoassays, In Vitro Assays, Laboratory Automation, Ligand Binding Assay, Liquid Chromatography-Mass Spectrometry (LC-MS), Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacotherapeutics

Preferred

Skills:

The salary range for this role is $87,300.00 - $

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at

You can apply for this role through  (or via the Workday Jobs Hub if you are a current employee). The Final date to receive applications for this position is stated on this posting.

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