Clinical Flow Cytometry Scientist

Contract Length: 1 year, potential for extension and conversion

Location:

Springhouse, PA 5x onsite

Hours:

40 hours

Start Date:

ASAP

We are seeking a passionate and talented laboratory-based scientist to join the Clinical Flow Cytometry group within Biomarker Development & Operations at a leading biopharmaceutical company in Spring House, PA. In this contractor role, you will support Oncology clinical programs by designing and executing robust ex vivo and in vitro cell-based and flow cytometric assays. The primary objective is to deliver fit-for-purpose flow cytometry biomarker assays and high-quality clinical data in a highly collaborative, fast-paced clinical research environment.

The ideal candidate must possess an expert level of hands‑on flow cytometry skill, particularly in designing complex panels independently. Rather than acting as a standard 'robotic' operator of pre-set assays, you will take complete end-to-end ownership—driving assay development, validation, troubleshooting, and scientific interpretation of complex, precious primary clinical trial specimens.

• Execute multi-parameter clinical flow cytometry biomarker assays end-to-end including assay development, optimization, fit-for-purpose validation, on-time assay deployment for clinical sample testing, and downstream analysis.
• Design, develop, and perform robust ex vivo and in vitro cell-based assays that incorporate functional readouts, including immune activation, cell proliferation, cytokine production, and cytotoxicity.
• Handle and isolate primary human cells from blood and cryopreserved specimens for deep phenotypic characterization and functional assessment.
• Record experimental data and results accurately and in a well-organized format, strictly adhering to Standard Operating Procedures (SOPs) and internal documentation standards (including writing comprehensive validation reports).
• Analyze, interpret, and present scientific data in professional, 'publication-ready' formats for internal stakeholders and project teams.
• Demonstrate professional verbal and written communication effectively presenting complex scientific findings, data patterns, and cytometric concepts to matrix-led teams.
• Support clinical flow cytometry research projects externally, collaborating with and coordinating studies implemented at external service providers and CROs.
• Monitor data quality from outsourced assays, performing rigorous assay troubleshooting to correct errors, identify root causes of analytical failures, and prevent re-occurrence.
• Work independently and manage multiple projects simultaneously, demonstrating strong organizational skill and self‑direction in the laboratory.
• Collaborate actively with multidisciplinary stakeholders from all relevant functions, and demonstrate the flexibility to contribute to scientific projects outside of your immediate core scope.

Candidates should meet the following minimum guidelines (note that overall scientific capability and hands‑on skill can adjust these standard baselines):

• Bachelor of Science (B.S.) with 3+ years of post‑degree laboratory experience in flow cytometry.
• Master of Science (M.S.) with 2+ years of post‑degree laboratory experience in flow cytometry.
• Doctor of Philosophy (Ph.D.) with 1+ years of post‑degree laboratory experience in flow cytometry.

• High‑Dimensional Panel Design (Required): Extensive, verified hands‑on experience independently designing, optimizing, and validating high-dimensional/multi‑color flow cytometry panels (double‑digit colors, ranging up to 30 colors). This is not a 'button‑pusher' role; you must understand panel building from scratch.
• Primary Human Cell…