Senior Scientist, Biology-Discovery

We're seeking an experienced Senior Scientist to join the Infectious Disease and Vaccines department at our research site in West Point, PA. The candidate will have a primary role on a team responsible for the discovery and development of novel antiviral treatments, with a particular focus on HIV. The candidate will independently design and execute hands on experiments to interrogate fundamental virus biology, virus host interactions, and immunological responses using various biochemical and cell based assays and in vivo disease models.

The candidate should have a strong background in virology, translational animal models, immunoassay and genomic technologies, cell biology, animal pharmacology, and general knowledge of infectious disease drug development and T cell biology. We value creative thinking, teamwork, and independent analytical problem solving. If you are a highly motivated team player with a strong desire to impact basic research and translational medicine, we invite you to consider joining our team.

BS/BA degree in Biology or Biomedical Sciences with a minimum 7 years of experience in industry and/or academia, or a MS degree in Biology or Biomedical Sciences with 4 years of experience in industry and or academia, or PhD with >1-year postdoctoral experience.

• Highly skilled in virology with expertise in a range of virological, molecular and cellular techniques, including in vitro and in vivo disease models.
• Experience with rodent handling and small animal procedures, including injections (IP, SQ, IV, PO), blood sampling (IV, RO), and tissue collection and analysis.
• Proficiency in HIV biology, including latency, and demonstrated rigorous productive research in investigative viral replication, virus host interactions, innate and adaptive immunity, and HIV pathogenesis.
• Proven track record in immunological and molecular techniques, including cell culture and T cell purifications, virus production, ELISA, flow cytometry, PCR, and has experience with animal pharmacology.
• Knowledgeable in drug discovery and translational research.
• Good communication (verbal & writing) skills with a track record of publications.
• Solid computer skills, independent experimental design and execution, analytical problem solving capabilities, and ability to work collaboratively in a multi-disciplinary team environment.
• Keen awareness of emerging biology and new technologies.

• Multi-parameter Flow cytometry andICS. Experience with instruments including BD Symphony, LSR II, and FACSARIA and Sony SH800 desirable.
• Knowledge of biomarker discovery and assay development as it relates to infectious diseases and immune responses, particularly 10X genomics or other immuno profiling platform experience.
• In vitro and ex vivo probing of tissues for host-pathogen responses using biochemical methods, cell based assays, and in vivo disease models, particularly for infectious disease.

Animal Models, Antiviral Drugs, Assay Development, Biochemical Assays, Biomarkers, Cell Culture Techniques, Drug Target Identification, Enzyme Linked Immunosorbent Assay (ELISA), Flow Cytometry, Immunoassays, Immunology, Infectious Disease Research, In Vitro Research, In Vivo Models, Molecular Biology, Pathogenesis, Tissue Collection, Transcriptomics, Virology

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment.

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