Principal Scientist, Veterinary Pathology Board Certified

Our Company is a leading global biopharmaceutical company with over 130-year history with an inspiring mission to make discoveries that positively impact global healthcare. Our success is driven by putting patients first, operating with the highest integrity, and committing fully to our vision to make a difference in the lives of people globally. With our different pipeline of oncology, immunology, vaccines, biologics, small molecules, and newer modalities, we are at the forefront of research to advance the prevention and treatment of diseases such as cancer, cardiometabolic diseases, neurodegenerative diseases, eye diseases, and infectious diseases.

Our Company's Research Laboratories’ nonclinical safety assessment group at the West Point, Pennsylvania site is seeking an anatomic pathologist to join a highly collaborative team of scientists (12 anatomic pathologists, 3 clinical pathologists, and approximately 40 exceptional laboratory scientists), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories. Our team works on a different and exciting pipeline, participating in a wide variety of GLP-toxicology study types, many of which are run in-house, in addition to early discovery and investigative studies.

Pathologists at our company are integral members and leaders of collaborative cross functional scientific teams, addressing challenges from early discovery to late development. Our Company’s pathologists provide scientific leadership in the design and conduct of postmortem evaluation of studies and integrate the interpretation of postmortem data into the safety profile of drug candidates. Our Company's pathologists have different opportunities to learn and grow as professional scientists and drug developers through daily study related activities and collaborative works with different program development teams.

• Employ routine H&E evaluations and specialized techniques to characterize the safety profile of new drugs from nonclinical toxicology and investigative studies
• Work independently to create and interpret data, and review relevant literature to determine the significance of postmortem results
• Opportunity for developing in role by gaining sufficient experience/training to serve as Therapeutic Area Pathology Lead, providing scientific input and oversight across studies from very early discovery to late-stage development, following molecules throughout their development cycle
• Communicate with study teams on postmortem findings and participate in projects to elucidate mechanisms of toxicity
• Provide scientific and technical guidance to technical staff
• Utilize tools and applications available on-site, including:
  • An industry-leading suite of on-site in vitro and in vivo assay capabilities
  • Access to robust historical control slide archive and database
  • Digital Pathology for primary and peer review pathology evaluations
  • Quantitative digital image analysis and targeted machine learning applications
  • Transmission electron microscopy
  • Special histochemistry, Immunohistochemistry and in situ hybridization
• Contribute to developing biomarkers and predictive models to de-risk drug candidates for safety-related liabilities

Our Company's pathologists have the opportunity to be mentored as nonclinical safety assessment leads on enterprise-level drug development teams:
Generating regulatory strategy Overseeing the design and execution of nonclinical toxicology studies Communicating with global regulatory agencies

Our Company's pathologists interact closely with each other, share slides and opinions, and help each other learn and grow

• Ability to collaborate with different cross-functional teams
• An opportunity mindset
• Doctor of Veterinary Medicine (DVM) ACVP or ECVP-board certification or equivalent in anatomic pathology

• PhD in Toxicology, Pathology, or related discipline
• Experience as a pathologist in biotech, pharma or CRO
• Knowledge of drug discovery, development and regulatory processes
• Demonstrated growth mindset and potential to contribute to broader scientific influence within a…