Principal Research Scientist

Job Description

The Genomics Research Center at Abb Vie is seeking a talented and motivated Principal Research Scientist to support our immunology clinical trials, pharmacogenetics and reverse translation efforts. This individual will contribute to studies aimed at understanding the biology of autoimmune diseases such as inflammatory bowel disease, psoriasis and rheumatoid arthritis. The ideal candidate will be detail-oriented and collaborate with cross‑functional teams to design, interpret, and deliver genomic analyses that inform our Immunology pipeline and deepen biological understanding of immunological diseases.

This role offers the opportunity to work with cutting‑edge genomic technologies in a dynamic and innovative environment.

• Provide scientific leadership and genomic expertise to immunology clinical trials, integrating genetics, transcriptomics, and other molecular data into trial design and analysis.
• Design and execute strategy and interpret clinical and real‑world data to derive mechanistic insights from clinical samples.
• Collaborate closely with discovery, clinical, biomarker, bioinformatics, and translational medicine teams to inform decision‑making and study objectives.
• Interpret complex multi‑omics datasets, integrating clinical outcomes with molecular profiles.
• Communicate findings clearly to both scientific and cross‑functional audiences through presentations, reports, and publications.
• Stay abreast of emerging scientific trends and technologies relevant to immunology and genomics, recommending their adoption when appropriate.
• Build external scientific connections which foster professional development and promote the reputation of the Genomics Research Center.

• BS or equivalent with typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience;
  PhD with typically 6+ years of experience in scientific area or discipline.
• Demonstrated experience (5+ years) supporting clinical or translational research in immunology or related therapeutic areas, preferably in an industry setting.
• Expertise in interpreting high‑dimensional genomics data (genetics, transcriptomics, single‑cell, etc.).
• Familiarity with omics databases and biobanks.
• Experience working with clinical trial design, biomarkers, or reverse translation strongly preferred.
• Excellent problem‑solving, project management, and communication skills.
• Ability to work collaboratively in a multidisciplinary, fast‑paced environment.

• PhD, MD/PhD, or equivalent in Genetics, Molecular Biology, Immunology or a related field.
• Previous industry experience in pharmaceutical or biotechnology companies.
• Experience in supporting target progression across discovery and development pipeline.
• Track record of scientific publications and presentations.

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range.
  
  This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short‑term incentive programs.
• This job is eligible to participate in our long‑term incentive programs.

Note:

No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

Abb Vie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer / Veterans / Disabled.

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