Analytical Scientist

Software Guidance & Assistance, Inc., (SGA), is searching for an Analytical Scientist for a contract assignment with one of our premier Pharmaceutical clients in Philadelphia, PA
.

Responsibilities :

• Seeking an analytical scientist to support routine automated testing of gene therapy research and development samples.
• Responsible for the day-to-day operation of high-throughput (HT) analytical methods to support development and characterization of recombinant Adeno-Associated Virus (rAAV) vectors for gene therapy development.
• Perform routine testing of vectors and process intermediates in cell-based potency assays, immunoassays (ELISA, gyros), and molecular assays (qPCR, dPCR) using automated liquid handlers (Tecan, Hamilton).
• Maintain cultures of multiple mammalian cell lines.
• Prepare and qualify laboratory reagents and materials for use in routine testing.
• Participate in sample management and cleanout activities, inventory management of reagents and materials, instrument maintenance, and verification & suitability assessments of laboratory equipment.
• Maintain good notebook documentation, perform data analysis, close-out experiments in a timely manner, monitor assay performance, and complete results/qualification reports.
• Comply with all SOPs, policies, and laboratory safety procedures.
• Job Function and Description - 80%:
  • Hands-on execution of multiple automated and/or manual analytical methods such as cell-based potency methods, immunoassays, and/or molecular assays to support gene therapy research and process development.
  • Routine cell culture maintenance of multiple cell lines
  • Preparation of reagents, raw materials, and buffers/media for analytical methods
  • Manage inventory of lab reagents/consumables and participate in sample and lab cleanouts
  • Support maintenance and verification/calibration of laboratory equipment in collaboration with the lab automation and metrology teams.
• Job Function and Description - 20%:
  • Use of analysis software such as Soft Max Pro, Graph Pad Prism, and custom in-house developed spreadsheets to perform data analysis
  • Documentation of all experiments in electronic notebooks and/or technical reports

Required
Skills
:

• A bachelor's degree or M. S. degree in biology, biochemistry, biomedicine, cell biology, or bioengineering.
• Minimum of 1 year of relevant work experience is required.
• Experience with aseptic technique and cell culture maintenance is required.
• General scientific knowledge of cell and molecular biology, biochemistry, and related analytical methods.
• Ability to learn new techniques and work independently once trained on protocols.
• Strong organizational and time-management skills
• Strong record-keeping and communication skills
• Comfortable working in a fast-paced, high throughput lab environment.
• Must value research integrity and collaborative research.
• Discuss process variations and/or out of range results with senior members of team and refer to policies/practices for guidance.
• Exercise judgment within defined procedures and practices to determine appropriate action.
• Must be comfortable in the fast-paced, biotech environment and interact with multi-Disciplinary teams
• High Throughput Analytics & Operations (HTAO) Team Members
• High Throughput Technologies & Lab Automation (HTLA) Team Members
• Cross-functional Team Members across Analytical Development and Technical Development organizations requires good written and verbal communication skills and the ability to work effectively in a team environment is a must.
• Position is a lab-based role and therefore requires the candidate to be on site the majority (> 80%) of time and to wear PPE as required by lab SOPs.
• Must be able to lift 25 pounds.
• Due to the inherent nature of cell-based assays, some weekend work and/or work on holidays may be needed. On occasion, long work hours may be required depending upon the testing schedule.

Preferred
Skills
:

• Experience with liquid handling automation platforms (Tecan Fluent, Hamilton STAR/ Vantage, etc.) is highly preferred.
• Experience with cell-based analytical methods and/or immuno-assays is highly preferred.

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it.

You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion ase find us at .

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our…