Research Investigator Sr

Research Investigator Sr.

The Penn Image-Guided Interventions (PIGI) Laboratory in the Departments of Radiology and Cancer Biology at the Perelman School of Medicine at the University of Pennsylvania is seeking a highly motivated and organized Senior Research Investigator. The PIGI Laboratory is an interdisciplinary translational research program operating at the intersection of cancer biology, molecular imaging, and image-guided interventions. The laboratory employs a multidisciplinary approach spanning molecular and cellular biology, cancer genetics, tumor immunology, cancer metabolism, animal models of cancer, advanced imaging technologies, and image-guided therapies, with the ultimate goal of developing novel diagnostic and therapeutic strategies for patients.

A major focus of the laboratory is understanding the biological mechanisms that govern response and resistance to locoregional therapies, including endovascular and percutaneous interventions, in hepatocellular carcinoma (HCC) and neuroendocrine tumors (NETs). Current research efforts emphasize characterization of the tumor microenvironment and its dynamic interactions with cancer cells, stromal elements, immune populations, and therapeutic interventions. The successful candidate will work closely with investigators in interventional radiology, cancer biology, pathology, immunology, and computational biology to develop and lead studies leveraging patient-derived models, clinical biospecimens, molecular profiling technologies, and preclinical models of cancer.

This position offers the opportunity to participate in an innovative and collaborative research environment, contribute to the strategic growth of a highly translational research program, supervise and mentor trainees and staff, and interact with a broad community of investigators within the Departments of Radiology and Cancer Biology, the Abramson Family Cancer Research Institute and the Abramson Cancer Center.