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Senior Scientist, Computational Safety & Exploratory Pharmacology

Job in Philadelphia, Philadelphia County, Pennsylvania, 19117, USA
Listing for: MSD Malaysia
Full Time position
Listed on 2026-07-29
Job specializations:
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 106200 - 167200 USD Yearly USD 106200.00 167200.00 YEAR
Job Description & How to Apply Below
Senior Scientist, Computational Safety & Exploratory Pharmacology Skip to main content
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Not Applicable locations:
USA
- Pennsylvania
- West Pointtime type:
Full time posted on:
Posted 8 Days Agotime left to apply:
End Date:
August 7, 2026 (11 days left to apply) job requisition :
R408085
** Job Description
** The Nonclinical Drug Safety (NDS) division at our company is seeking a motivated and talented biomedical engineer or integrative systems scientist with experience in signal processing and/or computational modeling using physiologic signals to join our Safety & Exploratory Pharmacology group.
The Safety & Exploratory Pharmacology (SEP) collaborates with our discovery research, preclinical, and clinical development partners to identify and develop effective, safe therapeutics. To that end, SEP utilizes a purposeful blend of standard screening tools, regulatory-enabling assays, fit for purpose capabilities and forward-looking innovative solutions to understand potential major organ system pharmacodynamic risk to influence drug development strategy.
To enhance that mission, we are looking for a MS or early-career PhD level individual contributor that will complement existing areas, expand the team’s expertise, and help drive future innovation. The successful candidate will have demonstrated experience in areas detailed below and will possess the attributes and interest in developing their career toward increasing levels of responsibility and independence within our team.
** Key responsibilities will include:
*** Analyzing physiologic signals to contribute to risk assessment evaluations and developing data visualizations for scientific exploration
* Building new in vivo analysis tools (signal processing, machine learning, AI) for nonclinical data and refining or developing new endpoints
* Working with external vendors to identify and incorporate potential solutions
* Collaborating with internal data science and IT teams to implement data tools
* Integrating new analysis workflows into SEP
* Contributing to SEP initiatives to develop and characterize novel alternative methods (NAMs) with in vitro scientists
*
* QUALIFICATIONS:

***
* Education:

*** Bachelor's (with 7+ years), Master's (with 4+ years) or Ph.D. in Biomedical Engineering, Bioengineering, Computational Biology, or related scientific field with relevant experience in the collection and computational analysis of physiologic signals (e.g. ECG, EEG, blood pressure) and a background in pharmacology, physiology, biology, biomedical sciences, or toxicology
** Required

Experience and Skills:

*** Experience with nonclinical signal analysis
* Proficiency with programming tools (Python, Mat Lab, R) for physiological signal analysis, feature extraction, and/or development of computational models (including AI tools and workflows)
* Previous experience working with physiological, continuous, time-series data sets (including visualization, analysis, and/or interpretation)
* Motivation and enthusiasm to expand programming/analysis skill set and learn new software tools
* Ability to work within teams as a contributor and enable collaborations across departments that deliver current needs and future capabilities
* Ability to collaborate with both laboratory…
Position Requirements
10+ Years work experience
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