Post-Doctoral Fellow - Lab of Dr. Tyagi

Postdoctoral Fellow Position

A highly motivated postdoctoral fellow is sought to join the laboratory investigating the molecular and cellular mechanisms underlying HIV persistence, neuroinflammation, accelerated aging, and neurodegeneration. The laboratory utilizes cutting-edge human induced pluripotent stem cell (iPSC)-derived microglia, cerebral organoids, and advanced genomic approaches to identify novel therapeutic targets and develop innovative interventions for HIV-associated and age-related neurological disorders. The successful candidates will participate in exciting multidisciplinary projects focused on understanding how HIV infection, chronic inflammation, and drugs of abuse alter brain function and contribute to neurocognitive impairment, neurovascular dysfunction, and accelerated aging.

Research experience (post-Doc Fellow) in the following areas:

• Human iPSC-derived microglia and other brain cells
• Generation and characterization of cerebral and brain organoids
• HIV infection and persistence in the central nervous system
• Neuroinflammation and inflammasome signaling
• Aging and age-associated neurodegenerative mechanisms
• HIV infection and latency models
• CRISPR/Cas genome engineering
• Single-cell RNA sequencing (scRNA-seq)
• Other common molecular and cellular biology techniques

Responsibilities (post-Doc Fellow):

• Have a great interest in research and learning
• Come everyday
• Design and conduct independent research projects
• Mentor students, junior and other laboratory personnel
• Analyze and interpret experimental data
• Prepare manuscripts
• Present findings at scientific meetings
• Involved in reagent ordering, storage, and organization.
• Assist with data collection and laboratory organization, and maintain detailed laboratory records
• Provide a very brief daily report in the evening about the lab activity of the day and planning for the next day

Qualifications (post-Doc Fellow):

Ph.D. in Neuroscience, Cell Biology, Molecular Biology, Immunology, Virology, Stem Cell Biology, Biomedical Sciences, or a related field. The candidate should have a strong publication record demonstrating research productivity.

Work Shift:

Workday Day (United States of America)

Worker Sub Type:
Regular

Employee Entity:
Thomas Jefferson University

Primary Location Address: 1020 Locust Street, Philadelphia, Pennsylvania, United States of America

Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.

Jefferson offers a comprehensive package of benefits for full-time and part-time colleagues, including medical (including prescription), supplemental insurance, dental, vision, life and AD&D insurance, short- and long-term disability, flexible spending accounts, retirement plans, tuition assistance, as well as voluntary benefits, which provide colleagues with access to group rates on insurance and discounts. Colleagues have access to tuition discounts at Thomas Jefferson University after one year of full time service or two years of part time service.

All colleagues, including those who work less than part-time (including per diem colleagues, adjunct faculty, and Jeff Temps), have access to medical (including prescription) insurance.