Post Doc

Computational Biologist Position

A computational biologist position is immediately available in the laboratory of Dr. Fadia Ibrahim in the Department of Biochemistry and Molecular Biology, at Thomas Jefferson University. Our research program is focused on studying the molecular mechanism of a novel co-translational RNA decay process "ribothrypsis" and investigating the role of RNA dysregulation in neurodegenerative diseases. Our research integrates molecular biology, biochemistry, innovative RNA sequencing technologies, and advanced computational approaches.

We are seeking a highly motivated computational biologist to support ongoing research projects, develop and implement bioinformatics tools and pipelines, and oversee the processing, management, and analysis of next generation sequencing (NGS) data.

Required Qualifications:

• Ph.D. in Computational Biology, Bioinformatics, Computational Sciences, or a related discipline.
• Proficiency in R and Python and in working in Linux/Unix environments with command line-based bioinformatics tools.
• Experience analyzing and interpreting NGS data, including RNA-Seq and Ribo-Seq, with expertise in data evaluation and visualization (e.g., differential expression, ribosome occupancy, poly(A) tail analysis, and modifications detection).
• Basic knowledge of molecular biology techniques and familiarity with biological data.
• Knowledge of statistical methods and their applications to biological datasets.
• Strong analytical, problem-solving, and quantitative skills, with the ability to collaborate effectively in a multidisciplinary team environment.
• Publication track-record in relevant fields.

Preferred Qualifications:

• Familiarity with NGS platforms, including Illumina and Oxford Nanopore Technologies.
• Demonstrated ability to integrate, mine, and analyze diverse large-scale biological datasets.
• Experience with commonly used bioinformatics resources, tools, and databases, including ENCODE, UCSC Genome Browser, Ensembl, Bioconductor, and NCBI databases.
• Experience managing computational servers and data storage and backup.
• Ability to formulate and develop scientific hypotheses that support ongoing research.
• Strong organizational, written, and verbal communication skills.

Interested applicants are invited to submit a single PDF containing their CV, a cover letter outlining their research experience and interests, and the contact details of three referees.

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Thomas Jefferson University

1020 Locust Street, Philadelphia, Pennsylvania, United States of America

Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.

Jefferson offers a comprehensive package of benefits for full-time and part-time colleagues, including medical (including prescription), supplemental insurance, dental, vision, life and AD&D insurance, short- and long-term disability, flexible spending accounts, retirement plans, tuition assistance, as well as voluntary benefits, which provide colleagues with access to group rates on insurance and discounts. Colleagues have access to tuition discounts at Thomas Jefferson University after one year of full time service or two years of part time service.

All colleagues, including those who work less than part-time (including per diem colleagues, adjunct faculty, and Jeff Temps), have access to medical (including prescription) insurance.