Research Investigator Sr

Research Investigator, Senior

The Department of Radiology at the University of Pennsylvania invites applications for a medicinal radio chemist to join our NINDS U19 Center Without Walls, a multidisciplinary program advancing next-generation radiopharmaceuticals for imaging targets such as alpha‑synucleinopathies and 4R tauopathies, which spans multiple academic institutions across the United States. Applicants with demonstrated familiarity with the Center’s radiochemistry infrastructure and collaborative workflows are preferred.

The successful candidate will play a central part in continuing and expanding ongoing Penn projects, developing and automating protocols for labeling small molecules and related entities with isotopes such as fluorine‑18 and carbon‑11. Responsibilities span the radiochemistry workflow from discovery through translational application, working seamlessly with Penn’s medicinal chemistry, biology, and imaging teams. This position offers the opportunity to extend Penn’s established expertise and ensure continuity in high‑impact translational radiochemistry.

• Develop and optimize novel radio chemical methods for labeling biomolecules and other chemical entities with PET isotopes (e.g., fluorine‑18, carbon‑11, and others).
• Devise, implement, and streamline automated radio synthetic workflows to support translational imaging projects.
• Collaborate with medicinal chemistry, biology, and (pre) clinical imaging teams to design and execute radiochemistry studies from discovery through (pre) clinical evaluation.
• Contribute to multidisciplinary project planning, data analysis, grant writing, and dissemination of results through presentations and publications.
• Other duties and responsibilities as assigned
• Position is contingent upon grant funding

• Doctor of Medicine, Doctor of Philosophy, and 5 to 7 years of postdoctoral experience is required.

Philadelphia, Pennsylvania

Perelman School of Medicine

$79,500.00 - $94,753.00 Annual Rate

Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job’s level. Internal organization and peer data at Penn are also considered.

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.

Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

• Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre‑tax dollars.
• Tuition: Take advantage of Penn’s exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here r dependent children are also eligible for tuition assistance at other institutions.
• Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre‑tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
• Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.
• Long‑Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and…