Faculty Position - Research Scientist in Cardiology, Cardiac Regeneration and Translational Cardiova

Job Title

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

• + Medical:
  Multiple plan options.
• + Dental:
  Delta Dental or reimbursement account for flexible coverage.
• + Vision:
  Affordable plan with national network.
• + Pre-Tax Savings: HSA and FSAs for eligible expenses.
• + Retirement:
  Competitive retirement package to secure your future.

Mayo Clinic Arizona is pioneering the future of cardiovascular care through transformational research in cardiac regeneration and translational cardiovascular science. Our Department of Cardiovascular Medicine seeks an exceptional research scientist to establish a cutting-edge program addressing fundamental challenges in cardiovascular disease through innovative approaches in regenerative medicine, cardio-oncology, or related translational research areas.

This position directly supports Mayo Clinic's transformational vision to shift healthcare from reactive treatment to predictive prevention, aligning with:

• Genesis Initiative:
  Revolutionizing transplant discovery and developing alternatives to cadaveric transplant through pioneering science in cellular engineering, advanced cell therapy products, and bioartificial organ systems.
• Precure Initiative:
  Developing platform products that enable prediction and prevention of diseases through biological signatures, real-time sensing technologies, and algorithmic approaches.
• Bold. Forward. Transformation:
  Accelerating the path from discovery to clinical treatment, leveraging AI and data intelligence to reimagine clinical trials and therapeutic development.

Our department has established significant research infrastructure in cardiac regeneration, with active programs focusing on cell-based therapy for ischemic heart disease, enhancement of hiPSC-derived cardiomyocyte regenerative potency, neonatal heart regeneration and molecular pathways regulating cardiomyocyte proliferation, and nanoparticle-based, cell-type specific drug delivery systems. Our diverse extramural and intramural funding portfolio, inclusive of four active NIH R01 grants totaling over $8 million, demonstrates significant investigator excellence and national competitiveness.

We seek an innovative investigator who will establish a complementary and symbiotic research program in cardiac regeneration, cardio-oncology, or related translational cardiovascular science areas that align with our department's strategic vision and existing research infrastructure.

Candidates should demonstrate technical excellence and a proven track record in cardiovascular research. We welcome applications from investigators in diverse but complementary research areas including:

• + MD, MD/PhD, or PhD in cardiovascular science, cell biology, developmental biology, bioengineering, oncology, or related field
• + Strong publication record in peer-reviewed journals with first or senior author publications in high-impact journals
• + Record of competitive extramural funding (NIH R01 or equivalent federal/foundation support) or clear trajectory toward independent funding
• + Experience with advanced research methodologies relevant to cardiovascular disease

• + Cardiac regeneration and tissue engineering
• + Cardiac valves regeneration and bioengineering
• + Cardiac electrophysiology and regenerative medicine
• + Cardio-oncology and cardiovascular complications of cancer therapies
• + Stem cell biology and cellular reprogramming
• + Gene therapy and genetic modification approaches
• + Cardiovascular immunology and inflammation
• + Bioengineering and biomaterials for cardiac applications

• + Experience with in-vivo models (small or large animal)
• + Proficiency in advanced molecular techniques (single-cell sequencing, CRISPR, optogenetics, etc.)
• + Collaborative research experience with clinical and/or translational programs
• + Track record in translational research with potential for clinical application
• + Experience with drug delivery systems or therapeutic development

+ Active research program supported by NIH or equivalent funding

+ Physician-scientists with substantial research portfolios are strongly encouraged to apply

+ Demonstrated commitment to team science and fostering an inclusive research environment

+ Proven ability to bridge basic science discovery with clinical translation

The Department of Cardiovascular Medicine at Mayo Clinic Arizona is one of the most dynamic and rapidly growing cardiovascular programs in the United States,…