Faculty Position: Cancer Cell Surfaceome/Novel Therapeutic Design Scientist
Listed on 2026-08-25
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Research/Development
Oncology Care, Research Scientist, Immunology Research, Clinical Research
Position Description
Mayo Clinic Comprehensive Cancer Center in Arizona invites applications for an open-rank faculty position with a commitment to advancing cancer research into clinical impact. Mayo Clinic Comprehensive Cancer Center in Arizona is building a world‑class research hub to transform cancer patient care through actionable target discovery and next‑generation therapeutic platforms. This initiative sits at the intersection of basic discovery science defining cell surfaceome mapping and immune‑antigen discovery, through the development of cellular therapeutics, vaccine manufacturing, immuno‑therapeutics, and theranostics, supported by strong clinical and clinical trial programs and strategic collaborations.
Qualified investigators will have a focus along the continuum from discovery science on the identification and characterization of cancer‑related epitopes and the associated immunologic response as the foundation of novel therapeutics for clinical deployment in the setting of cancer prevention in high‑risk individuals, early cancer detection, mitigation of nascent cancer progression (“cancer interception”), and therapeutic applications for established disease. Potential therapeutic designs include but are not limited to cellular therapeutics, vaccine modalities and radiotheranostics.
Position Description
Mayo Clinic Comprehensive Cancer Center in Arizona invites applications for an open‑rank faculty position with a commitment to advancing cancer research into clinical impact. Mayo Clinic Comprehensive Cancer Center in Arizona is building a world‑class research hub to transform cancer patient care through actionable target discovery and next‑generation therapeutic platforms. This initiative sits at the intersection of basic discovery science defining cell surfaceome mapping and immune‑antigen discovery, through the development of cellular therapeutics, vaccine manufacturing, immuno‑therapeutics, and theranostics, supported by strong clinical and clinical trial programs and strategic collaborations.
Qualified investigators will have a focus along the continuum from discovery science on the identification and characterization of cancer‑related epitopes and the associated immunologic response as the foundation of novel therapeutics for clinical deployment in the setting of cancer prevention in high‑risk individuals, early cancer detection, mitigation of nascent cancer progression (“cancer interception”), and therapeutic applications for established disease. Potential therapeutic designs include but are not limited to cellular therapeutics, vaccine modalities and radiotheranostics.
Role and Leadership Expectations The Research Scientist Will
- Participate in institutional initiatives aligned with Mayo Clinic and Mayo Clinic Comprehensive Cancer Center’s vision to Cure, Connect, and Transform cancer care through transformative science.
- Lead an independent, externally funded research program in developmental therapeutics for translational science focused within the continuum of cancer cell surfaceome mapping through novel cancer therapeutics. This may include:
- Identification and validation of novel tumor antigens (“neoantigens”) for applications in therapeutics and diagnostics (theranostics).
- Characterization of immunologic response to cancer‑related immunopeptidomics
- Contribute to the development of next‑generation therapeutic platforms such as immunotherapies, cellular therapies, and nucleic acid‑based vaccines
- Conduct/coordinate pre‑IND enabling research for acceleration of novel therapeutics into First‑In‑Human early phase clinical trials
- Contribute to the development of next‑generation therapeutic platforms focused on immunotherapies, cellular therapies, antibodies/nanobodies, radiopharmaceuticals and nucleic acid‑based vaccines.
- Collaborate across multidisciplinary teams to translate discoveries into clinical‑grade therapeutics with coordination of internal/external manufacturing processes.
- Actively engage in Mayo Clinic Comprehensive Cancer Center activities.
- Engage in enterprise‑wide collaborations across Mayo Clinic sites (Rochester, MN; Phoenix and Scottsdale, AZ;…
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