Senior Security Manager

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary The Senior Security Manager is a strategic leadership role reporting to the Director of Corporate Security. This role is responsible for the development, implementation, and oversight of comprehensive security programs across all company sites, with a specialized focus on physical security and executive protection. This position ensures the safety and security of personnel, assets, and facilities while maintaining a proactive approach to risk management, executive protection, and crisis response.

The role requires close collaboration with internal stakeholders, law enforcement, and external security partners to design and enforce policies that mitigate threats and ensure business continuity. The Senior Security Manager will lead a team of security professionals, manage vendor relationships, and oversee the deployment of physical and technological security measures.

Job Responsibilities Assist the Director of Security in conducting Threat Assessments and Threat Mitigation of individuals exhibiting threatening behaviors toward Caris Life Sciences or any of its employees.

Aids in maintaining 24/7/365 oversight of badging systems; alarm and surveillance systems, security personnel and all other physical security measures.

Responsible for the protection and physical security of executive leadership.

Manages onsite and remote security personnel to ensure all physical/technical/operational security policies, standards, and operating procedures are adhered to.

Conducts audits of all security systems to ensure proper maintenance, usage, and capabilities.

Assists as Lead Agent or Advanced Team lead for Personal Protection Details as needed or based on threat intelligence.

Assists the Director of Security with the creation, implementation, training, and maintenance of all policies and procedures within security and assigned teams/areas.

Assists the Director of Security with conducting risk assessments, managing contracted security personnel/hiring additional security personnel, and coordinating with relevant stakeholders such as our local, state and federal partners.

Ensures compliance with security policies and best practices.

Assists the Director of Security with background investigations, access control audits, and internal investigations.

Provides oversight of the Security Operations Center; makes recommendations on best practices, reviews/modifies standard operating procedures, establishes an intelligence analysis component to the Security Operations Center.

Coordinates state of Texas Private Security Bureau requirements such as training and internal audits. Maintains compliance records for Level III and Level IV security personnel.

Maintain working relationships with vendors and planning leadership to ensure proper expansion timelines and guidelines are met.

Supervises and assists TSCM vendor (technical surveilience counter measures)
Acts as a liason between Local Law enforcement and government agencies in regard to threat mitigation.

Acts as a liaison to HR/Legal in assistance with Caris investigations.

Assist in design, documentation, and implementation of physical security technology using structural drawings and as-builts.

Support end-users, vendors, and teams across multiple times zones.

Manage facilities/vendors during installations and…