Postdoctoral Associate in Structural Biology and Biophysics

Position Details

Position Information

Recruitment/Posting Title Postdoctoral Associate in Structural Biology and Biophysics Department Quantitative Biomedicine Inst Salary Details 63968 Offer Information

The final salary offer may be determined by several factors, including, but not limited to, the candidate's qualifications, experience, and expertise, and availability of department or grant funds to support the position. We also take into consideration market benchmarks, if and when appropriate, and internal equity to ensure fair compensation relative to the university's broader compensation structure. We are committed to offering competitive and flexible compensation packages to attract and retain top talent.

Benefits

Rutgers provides a comprehensive benefits package to eligible employees. The specific benefits vary based on the position and may include:

* Medical, prescription drug, and dental coverage

* Paid vacation, holidays, and various leave programs

* Competitive retirement benefits, including defined contribution plans and voluntary tax-deferred savings options

* Employee and dependent educational benefits (when applicable)

* Life insurance coverage

* Employee discount programs

Posting Summary

The Deaconescu Lab at Rutgers University has one opening for a postdoctoral researcher. The laboratory's interests lie primarily in microbial stress responses, with particular emphasis on responses to DNA damage, the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Brugger et al.

JBC (2023, 2024), Brugger et al. Nature Communications (2020), Dorich et al, Genes Development (2019), Vemu et al. Science (2018), Le TT et al. Cell (2018) etc. More information about the lab can be obtained at

Position Status Full Time Posting Number 25FA0742 Posting Open Date Posting Close Date

Qualifications

Minimum Education and Experience

A successful postdoctoral candidate should hold a PhD in structural biology, biochemistry, biophysics or related field and have an established track-record of publications in peer-reviewed journals, solid experience with protein biochemistry. Prior knowledge of crystallography and/or single-particle electron microscopy is highly desirable. Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required.

New Ph.D. graduates are particularly encouraged to apply.

Certifications/Licenses Required Knowledge, Skills, and Abilities

Proficiency in molecular biology, protein expression and protein purification, characterization of protein and protein-nucleic acids complexes using various biophysical methods (for example: EMSA, ITC, AUC, FLUORESCENCE ANISOTROPY, BLI, MST, CD etc.).

Experience with assay development and molecular microbiology a plus. Research experience in crystallography and cryo-electron microscopy (cryo-EM) is desirable, however not required. The selected candidate will obtain appropriate training in crystallization and crystallographic computing, microscope alignments, data acquisition, image processing and structure calculation using a variety of cryo-EM software. The candidate should be comfortable using Linux. Strong written and oral communication skills in English, as well as the ability to prepare scientific manuscriptsand grant proposals, work independently and collaborate with other scientists are required.

Preferred Qualifications Equipment Utilized

Standard laboratory equipment including Biorad NGC pure purification systems, Mosquito crystallization robot, centrifuges, PCR cyclers, Gel Doc and cell culture incubators. Kulczyk group has several Mac workstations suitable for scientific computing and general manuscript preparation. The Institute for Quantitative Biomedicine houses the state-of-the-art cryo-EM facility:
Thermo Fisher Scientific Talos Arctica cryo-EM equipped with a Summit K2 direct electron detector, Bio Quantumenergy filter and a Volta phase plate;
Aquilos 2 cryo-FIB/SEM;
Leica DM6 FS/EM cryo-CLEM system; NMR facility (Bruker 800 MHz and 700 MHz with cryoprobes and two 600 MHz spectrometers); mass spectrometry and super-resolution imaging facilities, and is the world headquarters of the Research Collaboratory for Structural Bioinformatics (RCSB) consortium and the Protein Data Bank (PDB).

Physical Demands and Work Environment Overview

The Deaconescu Lab at Rutgers University has one opening for a postdoctoral researcher. The laboratory's interests lie primarily in microbial stress responses, with particular emphasis on responses to DNA damage, the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Brugger et al.

JBC (2023, 2024), Brugger et al.…