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Lead Design Engineer

Job in Pittsburgh, Allegheny County, Pennsylvania, 15201, USA
Listing for: System One Holdings, LLC
Full Time position
Listed on 2026-06-28
Job specializations:
  • Engineering
    Biomedical Engineer, Mechanical Engineer, Product Engineer, Process Engineer
Job Description & How to Apply Below

Lead Design Engineer

Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the design, development, and optimization of advanced biomedical devices used in human-relevant experimental systems. This role focuses on device fabrication, process development, and manufacturability to enable robust, reproducible, and scalable production of experimental platforms. The position will contribute to both early-stage prototyping and advancement toward higher levels of technical maturity and deployment

  • Design, prototype, and refine biomedical devices and components supporting advanced experimental system
  • Develop and optimize fabrication processes to ensure consistency, quality, and scalability
  • Contribute to selection and evaluation of materials, fabrication methods, and assembly workflows
  • Perform testing and validation of device performance, including durability, reproducibility, and functional integrity
  • Collaborate with scientific and engineering teams to align device design with experimental requirements
  • Maintain documentation related to design iterations, fabrication processes, and quality control
  • Troubleshoot device-related issues and implement design improvements
  • Support coordination of engineering activities across multidisciplinary teams and contribute to project execution
  • Contribute to preparation of technical documentation, reports, and related materials
Requirements
  • Bachelor's degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field
  • Minimum of 3 years of relevant experience in device design, prototyping, or fabrication
  • Experience with engineering design tools (e.g., CAD software)
  • Strong problem-solving skills and attention to detail
  • Ability to work effectively in multidisciplinary research and engineering environments
Preferred Qualifications
  • Master's or Ph.D. in a relevant engineering discipline
  • Experience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling
  • Familiarity with polymer-based materials and manufacturing processes
  • Experience with iterative prototyping and design-for-manufacturing principles
  • Experience working at the interface of engineering and biological systems
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