Senior Scientist, Molecular & Viral Safety

Senior Scientist, Molecular & Viral Safety Skip to main content
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Not Applicable locations:
USA
- Pennsylvania
- West Pointtime type:
Full time posted on:
Posted Todaytime left to apply:
End Date:
June 26, 2026 (2 days left to apply) job requisition :
R389531
** Job Description
** The Molecular & Viral Safety group within Cell-Based Sciences is seeking a detail-oriented, technically skilled Senior Scientist to support daily operations in our Next Generation Sequencing (NGS) laboratory and contribute to multidisciplinary analytics. This hands-on role is ideal for someone with a strong background in molecular biology techniques and an interest in basic bioinformatics and computational workflows. The successful candidate will be responsible for executing established protocols for nucleic acid extraction, library preparation, sequencing, and will perform routine data processing and basic bioinformatics analyses.

The senior scientist will collaborate within a dynamic, integrated, and multidisciplinary team supporting both vaccine and biologics modalities and will contribute to the development and implementation of next‐generation sequencing technologies to help ensure that our products are free of adventitious agents as well as provide sequencing support to other priority programs of our Company.###
** Key Responsibilities
*** Perform DNA and RNA extraction from a variety of sample types (e.g., tissues, cell cultures, in-process samples) following standardized procedures.
* Prepare NGS libraries using automated and manual workflows for platforms such as Illumina and Oxford Nanopore Technologies.
* Operate, troubleshoot, and maintain laboratory instrumentation including sequencers, thermocyclers, and liquid handling robots.
* Perform quality control (QC) assessments using fluorometric quantification (e.g., Qubit), electrophoresis, and fragment analysis (e.g., Tape Station).
* Process raw sequencing data and perform routine bioinformatics tasks such as quality trimming, read mapping, basic variant calling, and generating summary metrics/reports using established pipelines.
* Execute and adapt basic command-line bioinformatics tools (e.g., FastQC, BWA/Minimap2, Samtools, bcftools) and utilize workflow managers or pipelines where applicable.
* Prepare, visualize, and interpret data outputs (e.g., coverage plots, QC summaries, variant tables) and communicate results to cross-functional teams.
* Work with bioinformatics colleagues to validate and implement new analysis pipelines and troubleshoot analysis issues.
* Utilize and be familiar with high-performance computing (HPC) environments, job schedulers (e.g., SLURM), and basic cluster file system concepts; transfer and manage sequencing data securely between local workstations and shared compute resources.
* Adhere to good laboratory practices (GMP), standard operating procedures (SOPs), safety policies, and quality assurance protocols to ensure accuracy, compliance, and reproducibility.
* Record, manage, and organize experimental data using electronic laboratory notebooks (ELNs) and other digital systems, ensuring data integrity and traceability of computational analyses.
* Support laboratory operations, including inventory management, ordering, and restocking of consumables and reagents.
* Contribute to…