Mechanical Engineer, Consumables

As a Staff Mechanical Engineer
, you will serve as a primary technical architect and design leader for our next generation of biotech platforms. You will bridge the gap between complex instrument hardware and high-volume biotech consumables. This role requires a deep technical expertise in plastics, fluidics, and consumables while steering cross‑functional teams through the full product lifecycle. You are not just designing parts; you are defining and driving the technical strategy that ensures our products are scalable, regulatory‑compliant, and revolutionary.

• High-Precision Consumables: Lead the architecture and design of complex biotech consumables, focusing on Injection Molded (IM) plastics
  , over‑molding, LSR and assembly techniques (ultrasonic welding, laser bonding).
• Fluidic Integration: Drive the development of fluidic and microfluidic systems by consulting with fluidic SMEs, ensuring seamless integration between consumable cartridges and permanent instrument hardware.
• Advanced Simulation: Utilize FEA, tolerance analysis, and CFD to predict part behavior and ensure robust performance under laboratory operating conditions.
• Regulatory Excellence: Design for compliance with ISO 13485, FDA 21 CFR Part 820 as well as RUO. Contribute to the creation of Design History Files (DHF).

• Concept to production: Take full ownership of critical subsystems from "napkin sketch" through high-volume manufacturing (HVM).
• DFX Leadership: Champion Design for Manufacturing (DFM) and Design for Assembly (DFA), working closely with toolmakers and CMOs to ensure tool designs and strategies are optimized.
• Vendor Management: Act as the primary technical point of contact for external molding partners and material suppliers, ensuring quality and performance standards are met.

• IP Generation: Identify and pursue patentable innovations in fluid handling, sealing technologies, and consumable‑to‑instrument interfaces.
• Root Cause Analysis: Lead complex failure analysis (FEA, SEM, etc.) for plastic components, identifying issues such as creep, stress cracking, or biocompatibility failures and implementing permanent corrective actions.

• Technical Mentorship: Directly mentor junior Engineers, fostering a culture of rigorous engineering discipline and creative problem-solving.
• Cross-Functional Bridge: Serve as the "mechanical voice" in rooms full of Biologists, Chemists, and Software Engineers to ensure the hardware meets the underlying science.

• Education: BS/MS in Mechanical Engineering.
• Experience: 10+ years of experience in mechanical design, with at least 5 years specifically in medical devices or biotech consumables.
• Plastics Expertise: Deep knowledge of thermoplastic resins (COC, COP, PC, PP), elastomers (TPE/TPU), and the nuances of high-volume injection molding.
• Tooling/Equipment: Experience with CAD (Solid Works/Creo), PDM systems, and simulation suites.
• Quality Systems: Familiarity with Risk Management (ISO 14971), FMEA, and Gage R&R.

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program.

During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

Pay Range $179,300 — $242,500 USD

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.
We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology,…