Mechanical Engineer, Consumables

Staff Mechanical Engineer, Consumables

What if your next design project wasn't just on new technology like a phone or domestic appliance but actually helped make cancer a thing of the past? At 10x Genomics, our mission is to accelerate the mastery of biology to advance human health. But that progress doesn't happen in a vacuum—it is driven by new technologies and the people with the courage to build them.

We are moving with incredible urgency. We recently celebrated a massive milestone with the official unveiling of our newest innovation:
Atera. This system is a prime example of how we use first principles to make the impossible possible, bringing high-impact single cell analysis to more researchers than ever before. To keep this momentum going, we are looking for a Staff Mechanical Engineer, Consumables who isn't afraid of "difficult." This isn't just about CAD tools and validation testing; it's about interdisciplinary collaboration and solving the intricate challenges that stand between us and the next medical breakthrough.

We believe that "WE" is more important than "ME." You'll work alongside world-class scientists and manufacturing experts to ensure our consumables integrate perfectly with the biological workflows that are changing the world. Whether you are optimizing high-volume injection molding or leading a design from concept to commercialization, your work will be the foundation for the next generation of cures. If you are a doer who loves a challenge and wants to build a lasting legacy, you'll find your home here.

We don't just follow the path set by others—we forge our own.

What You Will Be Doing

• Strategic Design & Technical Leadership High-Precision Consumables:
  Lead the architecture and design of complex biotech consumables, focusing on Injection Molded (IM) plastics, over-molding, LSR and assembly techniques (ultrasonic welding, laser bonding). Fluidic Integration:
  Drive the development of fluidic and microfluidic systems by consulting with fluidic SMEs, ensuring seamless integration between consumable cartridges and permanent instrument hardware. Advanced Simulation:
  Utilize FEA, tolerance analysis, and CFD to predict part behavior and ensure robust performance under laboratory operating conditions. Regulatory Excellence:
  Design for compliance with ISO 13485, FDA 21 CFR Part 820 as well as RUO. Contribute to the creation of Design History Files (DHF).
• End-to-End Project Ownership Concept to production:
  Take full ownership of critical subsystems from "napkin sketch" through high-volume manufacturing (HVM). DFX Leadership:
  Champion Design for Manufacturing (DFM) and Design for Assembly (DFA), working closely with toolmakers and CMOs to ensure tool designs and strategies are optimized. Vendor Management:
  Act as the primary technical point of contact for external molding partners and material suppliers, ensuring quality and performance standards are met.
• Innovation & Problem Solving IP Generation:
  Identify and pursue patentable innovations in fluid handling, sealing technologies, and consumable-to-instrument interfaces. Root Cause Analysis:
  Lead complex failure analysis (FEA, SEM, etc.) for plastic components, identifying issues like creep, stress cracking, or biocompatibility failures and implementing permanent corrective actions.
• Leadership & Mentorship Technical Mentorship:
  Directly mentor junior Engineers, fostering a culture of rigorous engineering discipline and creative problem-solving. Cross-Functional Bridge:
  Serve as the "mechanical voice" in rooms full of Biologists, Chemists, and Software Engineers to ensure the hardware meets the underlying science.

Minimum Requirements

• Education:
  
  BS/MS in Mechanical Engineering.
• Experience:
  
  10+ years of experience in mechanical design, with at least 5 years specifically in medical devices or biotech consumables.
• Plastics Expertise:
  Deep knowledge of thermoplastic resins (COC, COP, PC, PP), elastomers (TPE/TPU), and the nuances of high-volume injection molding.
• Tooling/Equipment:
  Experience with CAD (Solid Works/Creo), PDM systems, and simulation suites.
• Quality Systems:
  Familiarity with Risk Management (ISO 14971), FMEA, and Gage R&R.

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