P-Scientist II, Reagents Sustaining

Scientist I – Reagent Sustaining and Applications

We are seeking a Scientist I to join the Reagent Sustaining and Applications group. The role interfaces with R&D, Production, Marketing, and Support to provide the best products to our customers from pre‑launch to end of life.

• Lead efforts in testing new materials, tools, and workflows to improve 10x's state‑of‑the‑art products.
• Collaborate with key internal and external partners to troubleshoot and mitigate any issues that may arise in 10x's Chromium product line.
• Design and execute experiments to assess the impact of protocol, reagent, or process changes on 10x's assays.
• Perform statistical analyses on key assay and QC metrics.
• Update manufacturing documents and present results.

• BS, MS, or PhD in molecular biology, biochemistry, genetics, microbiology, analytical chemistry, or related fields.
• 5+ years (BS), 2+ years (MS), or 1+ years (PhD) of relevant experience in reagent or assay development and optimization, preferably in the biotechnology industry.
• Experience analyzing large‑scale single‑cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers.
• Ability to design and execute experiments to measure the impact of process improvements and/or formulation changes.
• Experience with a broad variety of molecular biology and analytical techniques including qPCR, nucleic acid isolation, plate readers, bioanalyzers, gel imagers, and real‑time PCR instruments.
• Experience with single‑cell assays including cell handling, library preparation, and downstream analysis.
• Experience investigating, identifying, documenting, communicating, and resolving quality control issues in a controlled manufacturing environment.
• Experience defining, documenting, communicating, and transferring new manufacturing workflows into controlled manufacturing environments.
• Meticulous attention to detail and a conscientious work ethic.

• Hands‑on experience with the 10x Chromium platform.
• Experience using statistical tools such as JMP or R to analyze complex data sets, create DOE experiments, and create data trending reports.
• Experience with bioinformatic analysis of next‑generation sequencing data from Illumina platforms.

Pay Range: $123,100 — $166,500 USD. The base pay will depend on factors such as skills and experience. This role is also eligible for equity grants, comprehensive health and retirement benefit programs, and an annual bonus program or sales incentive program.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.