Analytical Chemist; to Perm

Analytical Chemist (Contract to Perm)

Pleasanton, California, United States

Our client is an innovative, early-stage biotechnology company developing next-generation formulation technologies designed to dramatically improve the pharmacokinetic performance of small molecule therapeutics. By unlocking new delivery options and creating highly differentiated products, their proprietary formulation platform is transforming how critical therapies reach patients.

Operating in a fast-paced, highly collaborative startup environment, they offer a culture driven by scientific curiosity, hands-on impact, and rapid translation from the bench to the clinic.

We are seeking a hands-on, highly motivated Analytical Chemist to generate high-quality analytical data and help advance our client's core formulation technology platform. This is a high-impact, onsite role in a growing startup lab environment, where you will contribute directly to both day-to-day analytical execution and the ongoing build-out of their laboratory capabilities.

• Method Development:
  Develop, optimize, and qualify robust analytical methods (primarily HPLC/UPLC) for both drug substance and drug product.
• Early-Stage Validation:
  Execute fit-for-purpose method validation activities tailored for early-stage development programs.
• Formulation Support:
  Perform routine and complex analytical testing to directly support ongoing formulation development and optimization.
• Physicochemical Characterization:
  Conduct wet chemistry analyses (such as titrations) and perform key physicochemical characterization, including solubility testing, pH profiling, and dissolution.
• Solid-State Analysis:
  Apply solid-state characterization techniques as needed to analyze new drug forms.
• Troubleshooting:
  Troubleshoot analytical methods and instrumentation to ensure the highest standards of robustness and reproducibility.
• Data & Documentation:
  Analyze, interpret, and clearly document experimental data. Author technical reports, analytical methods, and internal documentation.
• Cross-Functional Collaboration:
  
  Partner closely with formulation scientists, process development engineers, and external CDMO/CRO partners.
• Lab Build-out:
  Actively support lab setup, equipment onboarding, and operational readiness in an evolving startup ecosystem.

• Education:
  
  Bachelor's or Master's degree in Chemistry, Analytical Chemistry, or a closely related scientific field.
• Experience:
  
  7–10 years of hands-on experience in pharmaceutical or biotech analytical development.
• Technical Expertise:
  Strong, demonstrable experience with HPLC/UPLC method development, validation, and advanced troubleshooting.
• Wet Chemistry & Characterization:
  Solid proficiency in wet chemistry techniques and familiarity with physicochemical and solid-state characterization.
• Startup Mindset:
  Exceptional data analysis, documentation, and technical writing skills with the ability to work independently in a fast-paced, nimble startup environment.

• Experience supporting early-stage CMC or 505(b)(2) drug development pathways.
• Familiarity with dissolution testing, impurity profiling, or formal stability studies.
• Technical exposure to LC-MS or other advanced analytical techniques.
• Past experience managing or transferring methods to external CROs/CDMOs.