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Principal Network Engineer

Job in Plymouth, Hennepin County, Minnesota, USA
Listing for: HISTOSONICS INC
Full Time position
Listed on 2026-08-25
Job specializations:
  • IT/Tech
    Systems Engineer, Network Engineer, Network Security
Salary/Wage Range or Industry Benchmark: 150000 - 185000 USD Yearly USD 150000.00 185000.00 YEAR
Job Description & How to Apply Below

If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.

Principal Network Engineer

Full Time Professional Plymouth, MN, US

10 days ago Requisition

Salary Range: $ To $ Annually

Histo Sonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, Histo Sonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women’s health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.

We offer an exciting work culture where cutting-edge science meets real-world application, and each team member’s contribution is important to our success in ensuring our physicians and their patients get what they need most.

Location: Plymouth, MN

Position Summary (Why this role matters):

The Principal Network Engineer is the senior-most individual contributor within the Histo Sonics network engineering function and a member of a larger, multi-site IT team supporting Histo Sonics as a whole. This is a hybrid position based out of the Plymouth, MN office. The role owns the design, operation, and reliability of the enterprise network across all sites, spanning office routing, switching, and wireless, site interconnectivity, data center networking, dedicated cloud connectivity, perimeter and segmentation controls, remote access, and physical security network infrastructure.

It leads network design and execution for new and expanded facilities and provides the primary technical execution behind network engagement with the AI and R&D Infrastructure team, a partnership owned by the Senior Director, Information Systems and Security. The role is the highest level of technical escalation for network infrastructure and sets technical direction and standards for the function.

Key Responsibilities (What you’ll do):

Network Architecture and Engineering

  • Design, deploy, administer, and maintain the enterprise network across all sites, including routing, switching, wireless, network access control, and IP address management.
  • Own corporate site interconnectivity, including wide area network and SD-WAN topology, carrier and circuit selection, redundancy and failover design, and inter-site capacity planning.
  • Design and administer data center and server room networking, including core and top-of-rack switching, high-availability topologies, and out-of-band management, and maintain dedicated connectivity to cloud platforms, including private interconnects and virtual network routing, in coordination with the System Administration function.

Network Security

  • Own the design, administration, and rule lifecycle of enterprise firewalls, including policy standards, change review, periodic rule base review, and segmentation between corporate, laboratory, manufacturing, guest, and product environments.
  • Design and administer DNS security, web and content filtering, intrusion prevention, and remote access, including site-to-site and client virtual private networking following zero trust principles.
  • Develop forward-looking network security plans and roadmaps supporting the organization’s security maturity objectives, in partnership with Information Security and under the direction of the Senior Director, Information Systems and Security.

Facilities, Data Center, and Physical Security Infrastructure

  • Plan, design, and execute network buildouts for new and expanded facilities, including low-voltage design, wireless surveys and validation, equipment specification, vendor coordination, and cutover planning.
  • Own the network and supporting infrastructure for physical security systems, including access control and video surveillance, partnering with Facilities…
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