Emergency Medicine Nurse Practitioner - Poplar Bluff, MO

Poplar Bluff Regional Medical Center is seeking an experienced Emergency Medicine Nurse Practitioner to join its Emergency Department team in Poplar Bluff, Missouri. This is an excellent opportunity to practice in a busy, well-supported community emergency department with strong physician collaboration, structured coverage, and a patient-centered care environment.

At Poplar Bluff Regional Medical Center, you’ll be part of Community Health Systems, a national network of regional hospitals with a shared mission to deliver high-quality care where it’s needed most — close to home.

• Annual Emergency Department volume of approximately 40,000 visits
• Level III Trauma Center
• 32-bed Emergency Department
• Physician coverage: 36 hours per day (12-hour shifts)
• Advanced Practice Provider coverage: 36 hours per day (12-hour shifts)
• Strong collaborative emergency medicine team environment

• Emergency Medicine Nurse Practitioner role
• Competitive compensation
• Strong physician and APP coverage model
• Community-based emergency department setting
• Preference given to candidates with Emergency Medicine experience

• Competitive compensation
• Commencement bonus
• Residency/Fellowship stipend (if applicable)
• Annual CME allowance
• Relocation assistance
• Licenses, dues, and subscriptions reimbursement
• Vacation, health, dental, and vision benefits

If you’re ready to take the next step in your career, we want to hear from you.
Apply today.

Send your CV and letter of interest to Barry Edsell at  or reach out directly with any questions at

Poplar Bluff Regional Medical Center is a 410-bed acute care hospital serving southeast Missouri as a regional medical center. The hospital provides comprehensive services, including emergency care, cardiology, orthopedics, general surgery, obstetrics and gynecology, oncology, nephrology, pulmonary and sleep medicine, wound care and hyperbaric services, and urology. The hospital also supports care delivery through outreach clinics offering family practice services in surrounding communities.

Poplar Bluff is the county seat of Butler County and serves as a regional hub for healthcare, education, and business in southeast Missouri. Nestled among the Ozark foothills, the community offers outdoor recreation, festivals such as the Black River Festival and The Butler County Fair, and a balance of small-town living with regional access.