Senior Research Assistant Vivo

Department Overview

The OHSU Knight Cancer Institute is a pioneer in personalized cancer treatment and research, led by Dr. Brian Druker, whose development of Gleevec transformed Chronic Myeloid Leukemia from a fatal disease to a manageable one and proved that targeted therapies can work. The institute focuses on precision oncology, the early detection, prevention, and treatment of cancer, and creating a welcoming and supportive environment for its caregivers, researchers, and support personnel.

Knight affiliates subscribe to three guiding principles: we are bold, we are supportive, and we work as a connected team in our fight to end cancer as we know it. We
¿ d love for you to join us!

Every Knight Cancer employee is expected to embody our guiding principles:

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team — We must leverage our collective brain power to conquer cancer because no one individual can do it alone

As a Senior Research Assistant
, you will be part of a collaborative project team focused on drug development. You will support laboratory research by assisting in research activities of the project where needed and as appropriate for your training and interest. You will help to design and implement experiments and will have independent responsibility for research studies. You will conduct research with minimal supervision. You will have a detailed knowledge of all aspects of laboratory research and need to be comfortable working both individually and in highly collaborative teams.

You should possess good organizational and interpersonal skills. You will contribute to the scientific direction and planning for experiments within the project. Major roles for you will involve providing support and working directly in experiments involving animal work, cellular and molecular biology experiments, assisting in experimental design, training scientists and supervising students and Research Assistants, maintaining laboratory space and supplies, assisting in various other research activities, and organizing samples, datasets and studies.

May be located in shared services/core or work directly under a Principal Investigator (PI) to include sample processing, assays, cell/tissue culture, animal studies, library research, data collection, recording transcription, etc.

Duties include:

• Conducts molecular, cellular, and animal-based research experiments with minimal supervision.
• Manages mouse colonies, including breeding, genotyping, recordkeeping, and experimental procedures.
• Coordinates multiple research projects and supports study planning, documentation, and publication efforts.
• Trains research staff and collaborates with internal research partners, including the Animal Research Core.
• Develops research methods, maintains operational continuity, and supports laboratory activities as needed.
• Laboratory organization and compliance

• Bachelor's in relevant field AND 1 year of relevant experience OR Equivalent combination of training and experience
• Experience with bioconjugation of biomolecules and biomolecule purification, general molecular biology techniques such as sample processing, cell culture, flow cytometry, DNA purification for mammalian cell cultures, PCR, gel electrophoresis, plate readers, western blot
• Ability to operate complex scientific equipment and develop and troubleshoot complex experimental protocols
• Must possess energy and drive to coordinate multiple projects simultaneously: prioritize, schedule, manage and coordinate
• Demonstrated ability to undertake research and project…