Biotechnologist; NIGHTS

Biotechnologist (NIGHTS, All Experience Levels) – Cell Therapy & Mammalian Manufacturing

Shift differentials are available for Night and weekend hours worked.

Location:

Portsmouth, NH, USA. The actual location of this job is in Portsmouth, NH, USA.

At Lonza Portsmouth, you won’t just make medicine — you will help shape the future of how it is made. Our site is uniquely positioned at the intersection of personalized Cell Therapy and large‑scale Mammalian biologics manufacturing. In one facility, we produce both patient‑specific, life‑saving cell therapies and high‑volume biologic medicines used by people around the world. That means your career here doesn’t live in a single box — it grows across platforms, technologies, and modalities.

• Meaningful Patient Impact: From individualized therapies made from patient‑donated cells to large‑scale biologics produced in 2,000L, 6,000L, & 20,000L bioreactors, everything you do directly supports our purpose.
• Cross‑Platform Career Growth: As Lonza expands both Cell Therapy and Mammalian manufacturing, you’ll have opportunities to grow across modalities, technical depth, and leadership tracks.
• World‑Class Training: Develop expertise in Grade B aseptic gowning, cell therapy processing, and large‑scale mammalian systems (Upstream & Downstream).
• Comprehensive Benefits: Medical, dental, vision, 401(k), and global Lonza benefits:

Your responsibilities will scale with your experience and may span both Cell Therapy and Mammalian Manufacturing depending on business needs and your career path.

• Work in Grade B clean rooms requiring full sterile gowning.
• Perform aseptic processing inside laminar flow hoods using strict sterile technique.
• Receive, process, expand, and cryopreserve patient‑derived primary cells.
• Execute flawless cGMP documentation for individualized patient batches.

• Operate mammalian cell culture bioreactors (2,000, 6,000, and 20,000).
• Execute both upstream and downstream processes.
• Set up, operate equipment, and monitor production processes, including clean‑in‑place (CIP) and steam‑in‑place (SIP) operations and report production in written and electronic documents in accordance with good manufacturing practice (GMPs) and good documentation procedures (GDPs).
• Conduct in‑process testing pH, conductivity, metabolites, etc.

We hire across all experience levels and build teams that grow together.

• Foundational / Early‑Career : No prior biotech experience required. We look for high attention to detail, reliability, and an interest in learning a highly specialized life‑science trade.
• Intermediate (Level II / III): 1–5 years of experience in regulated manufacturing or clinical labs. Experience with aseptic technique, clean rooms, or bioreactors is a plus.
• Advanced / Senior: 5+ years of GMP experience. Track record of leading complex operations, mentoring others, and owning deviations.
• Education: High School Diploma required for all levels;
  Associate’s or Bachelor’s in STEM preferred for intermediate and advanced roles.
• Schedule: Ability to work a rotating 12‑hour shift (Night 7 PM – 7 AM). Our rotation follows a predictable pattern:
  Work 2 days on, 2 off, 3 on, 2 off, 2 on, 3 off. This ensures consistent time off and includes every other weekend.

Lonza is one of the world’s largest and most trusted CDMOs, with 30+ sites across five continents. Portsmouth is special— it’s one of the few places in the industry where cutting‑edge cell therapy and large‑scale biologics live side‑by‑side. Here, you don’t just fill a role—you build a career platform that can take you anywhere in biopharma.

Ready to help manufacture the future of medicine? Apply now.