Director, Transformation Office Portfolio Manager

At Genmab, we are dedicated to building extra[not]ordinary futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

The Director, Transformation Office Portfolio Lead is a key role within Genmab’s Transformation Office (TO). The Director will be the central orchestrator for operational and strategic initiatives, including initiative intake, prioritization, governance, reporting, and portfolio performance management. You will ensure that Genmab's most strategic initiatives are aligned with organizational priorities and deliver measurable business value. The initial focus of the Transformation Office is on R&D and Tech Ops (approximately 2,000 FTE), with potential for future scope expansion across the enterprise (~3,000 FTE).

The Transformation Office Portfolio Lead partners closely with senior business leaders, initiative sponsors, project managers, finance business partners and functional teams to drive rigorous initiative portfolio management, accelerate execution, and provide transparency on progress, risks, dependencies, and value realization. As a key driver of the Transformation Office, the Director will lead initiative portfolio management processes, develop recommendations on initiative prioritization, sequencing, and TO resource allocation, and ensure decisions are translated into action to maximize organizational impact.

The Director, Transformation Office Portfolio Lead will report directly to Head of the Transformation Office (currently the SVP, Global Head of PPM & R&D Operations). The position can be located in Plainsboro, NJ, Utrecht, NL or Copenhagen, DK.

• Own portfolio management for cross‑functional transformation initiatives that support Genmab’s financial commitments and strategic objectives
• Support the Transformation Office’s goals and objectives, aligned with the company’s overarching strategy and 2030 Vision
• Lead initiative intake screening, categorization, and prioritization processes, ensuring consistent application of prioritization criteria and governance framework
• Support, challenges and monitor projects, initiatives, and analyses focused on company transformation and productivity gains to inform strategic capital allocation and resourcing decisions
• Collaborate closely with Finance on Genmab’s long‑range financial plan and annual budget cycle
• Drive the organization’s ongoing mindset shift toward productivity and prioritization
• Drive execution of initiatives from initiation through closure, ensuring clear ownership, milestones, and follow‑through
• Track, report, and communicate TO initiatives to major stakeholders at all governance levels, including progress, risks, dependencies, and value realization
• Define, establish, and continuously monitor Transformation Office portfolio KPIs and success measures, ensuring transparent reporting of initiative performance, value realization, and overall portfolio health
• Lead the coordination and preparation of TO meetings and serve as meeting moderator
• Report on industry trends and peer company developments, translate their impact on Genmab, and improve overall strategic decision‑making quality
• Work cross‑functionally with R&D, Tech Ops, Commercialization, Finance, Human Resources, DD&AI, and other teams to drive alignment and execution

• A minimum of 15 years of relevant experience with a Bachelor's degree is required; alternatively, 12 years of relevant experience with a…