Senior Scientist

Responsibilities:

• Conduct routine in-vitro ADME assays.
• Plan, perform, and report in vitro metabolism ADME studies for discovery and development stage compounds.
• Participate in experimental design; perform experiments; critically analyze, interpret, and report data to define next steps.
• Complete high-impact and high-throughput studies in a fast-paced environment while managing multiple projects to meet timelines.
• Establish new ADME assays and contribute to continuous improvement of existing assays.
• Guide junior scientists.
• Assist with data analysis and interpretation.
• Provide laboratory support (ordering, equipment calibration/validation) while adhering to the Quality System.
• Work with Project Managers to meet client requirements.
• Assist in running and maintaining robotic systems.
• Perform quality review of peer data; help consolidate assay control and validation criteria.
• Perform other duties as assigned.

• PhD in a scientific relevant field (Ph.D. preferred) with experience in contract research organizations, pharmaceutical industries, or academia; OR Master’s with 6+ years of experience.
• Equivalent education and experience acceptable.
• Industry/academic experience in DM/PK with a strong record of scientific achievement.
• Experience in drug discovery/development.
• Broad understanding of ADME, in vitro drug metabolism, and DDI.
• Knowledge of bioanalytical sciences including LC-MS/MS, GC-MS, biotransformation, and physical organic chemistry.
• Experience with cell-based or biochemical assays.
• Excellent oral and written communication; strong attention to detail.
• Proficiency with Microsoft Word and Outlook.
• Ability to manage time and work independently; communicate with peers and all levels of management.

• Plate-based screening; cell culture experience; LC-MS/MS experience.