Director, Global Medical Evidence Generation Lead, Oncology

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits.

This is work that transforms the lives of patients, and the careers of those who do it.

The Director of Medical Evidence Generation in Medical Affairs will lead the strategic development and execution of a robust evidence generation plan including Medical Affairs Sponsored Trials (MAST), Clinical Research Collaborations (CRCs), and Investigator-Sponsored Research studies (ISRs) for an important asset within the Oncology portfolio across various tumor types. These studies will be designed to:

• Uncover new clinical development opportunities that will maximize the benefit our medicines can bring to patients
• Address important unmet needs that are gaps in the current clinical development plan
• Generate practice informing data to advance patient care

This will be a scientific and strategic leader collaborating across internal functions (Medical Strategy, Clinical Development & Operations, HEOR, RWE/Epidemiology, Access & Value, Regulatory) and external investigators.

• Define and drive the integrated evidence generation strategy aligned with Medical Affairs and overall product strategy, spanning clinical trials (Phase II/IV), real-world evidence (RWE), non-interventional studies, registries, observational research, and health outcomes studies.
• Critically assess the design of research concepts to ensure they are strategically aligned to BMS priorities and can achieve the stated objectives.
• Lead or significantly contribute to protocol development, including study design, study objectives and endpoints, eligibility criteria, statistical considerations (in collaboration with Biostatistics), and operational feasibility. Engage in peer-to-peer scientific dialogue with external research partners on collaboration studies to optimize key study design elements.
• Be accountable for delivering studies from concept ideation through governance approval and ultimately data readout.
• Serve as a thought leader on evidence generation methodologies to ensure evidence plans are fit-for-purpose and impactful.
• Lead preparation and delivery of evidence generation proposals and updates including results to internal governance bodies and cross-functional stakeholders.
• Apply strong understanding of GCP, ICH guidelines, and clinical trial governance to ensure compliant and high-quality study execution.
• Partner with Clinical Operations and CROs to ensure studies are delivered on time, on budget, and with high data quality.
• Participate in advisory boards, steering committees, and scientific forums as necessary.
• Collaborate with cross-functional partners to ensure cohesive planning and execution of evidence generation activities across geographies and therapeutic areas.
• Contribute to scientific dissemination through review of publications (manuscripts, abstracts and congress presentations) and advisory boards

• Advanced scientific degree (MD, PhD, PharmD, MS or the equivalent) required with extensive, relevant scientific, and/or strong clinical development experience.
• At least 5 years of experience in pharmaceutical clinical development, Medical Affairs, and/or relevant experience
• Deep understanding of clinical research and evidence generation methodologies
• Deep oncology therapeutic area expertise
• Demonstrated ability to…